Atogepant Impurity 81 CAS CATO-C4X-328581
| CAS No. | CATO-C4X-328581 |
| Molecular Formula | C27H22F3N5O3 |
| Molecular Weight | 521.49 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 521.49 g/mol gives Atogepant Impurity 81 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Atogepant Impurity 81 (CAS CATO-C4X-328581) is a certified pharmaceutical impurity reference standard with the molecular formula C27H22F3N5O3 and a molecular weight of 521.49 g/mol.
Atogepant Impurity 81 (C27H22F3N5O3) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Atogepant Impurity 81 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C27H22F3N5O3 |
| Molecular Weight | 521.49 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | ≥95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 18.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 5 |
Related Atogepant Standards
- Atogepant Impurity 59 (CAS CATO-C4X-328559)
- Atogepant Impurity 60 (CAS CATO-C4X-328560)
- Atogepant Impurity 61 (CAS CATO-C4X-328561)
- Atogepant Impurity 62 (CAS CATO-C4X-328562)
- Atogepant Impurity 63 (CAS CATO-C4X-328563)
- Atogepant Impurity 64 (CAS CATO-C4X-328564)
- Atogepant Impurity 65 (CAS CATO-C4X-328565)
- Atogepant Impurity 66 (CAS CATO-C4X-328566)
Recommended Standards
- 1,2-Bis(1-(7-chloroquinazolin-4-yl)piperidin-4-yl)ethane (CAS 52791-50-1)
- 2-(4-Benzhydrylpiperazin-1-yl)-N-(3,5-bis(trifluoromethyl)phenyl)acetamide (CAS 1024383-73-0)
- 2-((3,4-Dichlorobenzyl)thio)-4-(3,4-dimethoxyphenyl)-6-(p-tolyl)nicotinonitrile (CAS 444156-97-2)
- (4-(2-(4-((Tert-butyldiphenylsilyl)oxy)piperidin-1-yl)ethoxy)-3-fluorophenyl)boronic acid (CAS 1704082-87-0)
- Estetrol Impurity 6 (CAS CATO-C4X-32506)
- Tolvaptan Impurity 13 (CAS CATO-C4X-195513)
- Ibandronic Impurity 19 (CAS CATO-C4X-224419)
- Ethyl 1-(1-methyl-2-oxo-1,2-Dihydropyridine-4-carbonyl)piperidine-3-carboxylate (CAS 1153394-19-4)
- 5-Oxo-1-(4-propoxyphenyl)pyrrolidine-3-carboxamide (CAS 1706463-29-7)
- 4-Amino-3-methylbenzo[d]isoxazol-5-ol (CAS 329349-67-9)
- 8-Methoxy-2-phenylquinoline (CAS 393109-89-2)
- (E)-N-(3,4-Dichlorophenyl)-N'-methyl-3-(trifluoromethyl)benzene-1-carboximidamide (CAS 339028-27-2)
- (Oxybis(2,1-phenylene))bis(trimethylsilane) (CAS 18055-73-7)
- Semaglutide (CAS 910463-68-2)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com