Atogepant Impurity 61 CAS CATO-C4X-328561
| CAS No. | CATO-C4X-328561 |
| Molecular Formula | C21H23F9N2O3 |
| Molecular Weight | 522.40 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Atogepant Impurity 61 (CAS CATO-C4X-328561) is a certified pharmaceutical impurity reference standard with the molecular formula C21H23F9N2O3 and a molecular weight of 522.40 g/mol.
The molecular framework of Atogepant Impurity 61 (C21H23F9N2O3) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C21H23F9N2O3 |
| Molecular Weight | 522.40 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Atogepant Standards
- Atogepant Impurity 59 (CAS CATO-C4X-328559)
- Atogepant Impurity 60 (CAS CATO-C4X-328560)
- Atogepant Impurity 62 (CAS CATO-C4X-328562)
- Atogepant Impurity 63 (CAS CATO-C4X-328563)
- Atogepant Impurity 64 (CAS CATO-C4X-328564)
- Atogepant Impurity 65 (CAS CATO-C4X-328565)
- Atogepant Impurity 66 (CAS CATO-C4X-328566)
- Atogepant Impurity 81 (CAS CATO-C4X-328581)
Recommended Standards
- 2-[(2H-1,3-Benzodioxol-5-yl)methylidene]-N,N'-bis[4-(trifluoromethyl)phenyl]propanediamide (CAS 866008-52-8)
- 7-(3-bromo-4-methoxybenzyl)-1-ethyl-8-(((1R,2R)-2-hydroxycyclopentyl)amino)-3-(2-hydroxyethyl)-3,7-dihydro-1H-purine-2,6-dione (CAS 569351-91-3)
- 6-[Bromoacetamido]tetramethylrhodamine (CAS 166442-39-3)
- 5-[Bromoacetamido]tetramethylrhodamine (CAS 166442-38-2)
- Capivasertib Impurity 27 (CAS 3067887-26-4)
- Lafutidine Impurity 2 (CAS 174583-84-7)
- Epinephrine Impurity 8 HCl (Mixture of Diastereomers) (CAS 3198-07-0)
- 1H-pyrazolo[3,4-c]pyridin-4-amine (CAS 2231676-24-5)
- 1-(2,5-Dichlorothiophen-3-yl)ethan-1-amine (CAS 603951-46-8)
- N-Acetyl-N-{16,18-dioxo-17-azapentacyclo[6.6.5.0^{2,7}.0^{9,14}.0^{15,19}]nonadeca-2(7),3,5,9(14),10,12-hexaen-17-yl}acetamide (CAS 157543-75-4)
- 4-Bromo-3-chloro-2-methylbenzaldehyde (CAS 1224604-13-0)
- (3-Amino-5-methoxybenzofuran-2-yl)(phenyl)methanone (CAS 328276-62-6)
- 4-{5-[2-(5-Methoxy-1H-indol-3-yl)-2-oxo-ethylidene]-4-oxo-2-thioxo-thiazolidin-3-yl}-benzonitrile (CAS 1380572-61-1)
- Semaglutide impurity 257 (CAS CATO-C4X-2226257)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com