Gemigliptin impurity 1 CAS CATO-C4X-33061
| CAS No. | CATO-C4X-33061 |
| Molecular Formula | C18H17F8N5O |
| Molecular Weight | 471.35 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a process- or degradation-related impurity, Gemigliptin impurity 1 (CAS CATO-C4X-33061, C18H17F8N5O) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, Gemigliptin impurity 1 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 471.35 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO manufactures Gemigliptin impurity 1 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C18H17F8N5O |
| Molecular Weight | 471.35 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 5 |
Related Gemigliptin Standards
Recommended Standards
- BX-912 (CAS 702674-56-4)
- Lifitegrast Impurity N12 (CAS 851785-70-1)
- 1-(4-{[2-oxo-5-(trifluoromethyl)-1,2-dihydropyridin-1-yl]methyl}phenyl)-3-[4-(trifluoromethoxy)phenyl]urea (CAS 339025-59-1)
- 1-(3-Chlorobenzenesulfonyl)-5-[(E)-1-(4-chlorophenoxy)-2-phenylethenyl]-1H-pyrazole (CAS 400087-39-0)
- Tofacitinib Impurity 134 (CAS CATO-C4X-1079134)
- Daprodustat Impurity 31 (CAS CATO-C4X-240731)
- Phloroglucinol impurity 45 (CAS 634-94-6)
- 2-methyl-N1-(phenylmethyl)-1,2-Propanediamine (CAS 80704-02-5)
- 2-(2,4-Dimethoxyphenyl)isonicotinic acid (CAS 1258612-81-5)
- N-Methoxy-N-methylnaphthalene-1-carboxamide (CAS 226931-26-6)
- Ethyl 4-(1H-imidazol-2-yl)piperidine-1-carboxylate (CAS 1198420-87-9)
- 3-(Methoxymethyl)cyclobutanamine hydrochloride (CAS 1699607-79-8)
- 5-Amino-1-isobutyl-4-methylpyridin-2(1h)-one (CAS 1515306-02-1)
- (D-Tyr1,N-Me-Phe3)-Neuropeptide FF (H-4752.0001) (CAS 145274-93-7)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com