Capivasertib Impurity 44 CAS CATO-C4X-331244
| CAS No. | CATO-C4X-331244 |
| Molecular Formula | C33H38ClN11O3 |
| Molecular Weight | 672.18 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, Capivasertib Impurity 44 is typically pale yellow to yellow amorphous powder. Its solid-state physicochemical attributes — including a molecular weight of 672.18 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a process- or degradation-related impurity, Capivasertib Impurity 44 (CAS CATO-C4X-331244, C33H38ClN11O3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Capivasertib Impurity 44 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C33H38ClN11O3 |
| Molecular Weight | 672.18 g/mol |
| Purity | ≥95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 20.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 11 |
Related Capivasertib Standards
- Capivasertib Impurity 43 (CAS CATO-C4X-331243)
- Capivasertib Impurity 9 (CAS CATO-C4X-33129)
- Capivasertib Impurity 33 (CAS CATO-C4X-331233)
- Capivasertib Impurity 49 (CAS CATO-C4X-331249)
- Capivasertib Impurity 37 (CAS CATO-C4X-331237)
- Capivasertib Impurity 38 (CAS CATO-C4X-331238)
- Capivasertib Impurity 34 (CAS CATO-C4X-331234)
- Capivasertib Impurity 10 (CAS CATO-C4X-331210)
Recommended Standards
- 3-(2-(2,4-Di-tert-pentylphenoxy)acetamido)-N-(5-oxo-1-(2,4,6-trichlorophenyl)-4,5-dihydro-1H-pyrazol-3-yl)benzamide (CAS 31188-91-7)
- 2-[2-(2-Chloro-1,1,2-Trifluoroethoxy)Phenyl]-5-[[4-(Hexadecylsulphonyl)Phenyl]Amino]-2,4-Dihydro-3H-Pyrazol-3-One (CAS 84100-61-8)
- N-(2-(6-Ethyl-7-(p-tolyloxy)-3H-pyrazolo[1,5-b][1,2,4]triazol-2-yl)propyl)-2-(octadecyloxy)benzamide (CAS 142859-67-4)
- AZD-5991, >98% (HPLC) (CAS 2143061-81-6)
- Lomerizine Impurity 1 (CAS 1516207-30-9)
- Methyldopa Impurity 14 (CAS CATO-C4X-169314)
- Propranolol Impurity 7 (CAS 34646-56-5)
- 1-(10H-Phenothiazin-10-yl)-2-phenylethan-1-one (CAS 54012-72-5)
- ((2-Bromo-5-methoxybenzyl)oxy)(tert-butyl)dimethylsilane (CAS 511277-90-0)
- (6Z,9Z,12Z)-hexadeca-6,9,12,15-tetraenoic acid (CAS 86995-95-1)
- [1,1'-Biphenyl]-3,4',5-tricarbaldehyde (CAS 187281-19-2)
- 8-Fluoro-2,2-dimethylchroman-6-ol (CAS 2489411-91-6)
- 4-Chloro-3-ethyl-1-methyl-1H-pyrazole-5-carbonyl chloride (CAS 129560-00-5)
- Bradykinin-Like Neuropeptide (Aplysia californica) (H-1654.0001) (CAS 165174-60-7)
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