Capivasertib Impurity 33 CAS CATO-C4X-331233
| CAS No. | CATO-C4X-331233 |
| Molecular Formula | C27H35ClN8O3 |
| Molecular Weight | 555.07 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Capivasertib Impurity 33 is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies Capivasertib Impurity 33 (CAS CATO-C4X-331233), a pharmacopoeial impurity reference standard (molecular formula C27H35ClN8O3, MW 555.07 g/mol) used for the identification and quantification of trace impurities in APIs.
Structurally, Capivasertib Impurity 33 (C27H35ClN8O3) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 14.0, corresponding to approximately 14 ring(s) or double-bond equivalent(s). With a molecular weight of 555.07 g/mol, it falls into the moderately-high-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Capivasertib Impurity 33 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C27H35ClN8O3 |
| Molecular Weight | 555.07 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 8 |
Related Capivasertib Standards
- Capivasertib Impurity 49 (CAS CATO-C4X-331249)
- Capivasertib Impurity 37 (CAS CATO-C4X-331237)
- Capivasertib Impurity 38 (CAS CATO-C4X-331238)
- Capivasertib Impurity 34 (CAS CATO-C4X-331234)
- Capivasertib Impurity 3 (CAS CATO-C4X-33123)
- Capivasertib Impurity 4 (CAS CATO-C4X-33124)
- Capivasertib Impurity 29 (CAS CATO-C4X-331229)
- Capivasertib Impurity 35 (CAS CATO-C4X-331235)
Recommended Standards
- 870532-86-8 Bis(dodecylsulfanylthiocarbonyl) disulfide DTXSID40470687 (CAS 870532-86-8)
- (S)-1-(2-((tert-Butyldimethylsilyl)oxy)-1-(4-chloro-3-fluorophenyl)ethyl)-4-(2-((1-methyl-1H-pyrazol-5-yl)amino)pyrimidin-4-yl)pyridin-2(1H)-one (CAS 1453854-96-0)
- Fluticasone Furoate Impurity 4 (CAS CATO-C4X-32544)
- Dabrafenib Impurity 16 (CAS CATO-C4X-303316)
- Macitentan Impurity 24 (CAS 556797-16-1)
- Ambroxol Impurity 22 (CAS CATO-C4X-108522)
- Ketoprofen Impurity 46 (CAS 713-36-0)
- 3-((3,4-Difluorophenyl)thio)propanal (CAS 1341477-06-2)
- 3-Chloro-N-(2-isopropyl-6-methylphenyl)propanamide (CAS 546079-44-1)
- 2-Bromo-4-chloro-6-fluoro-1H-benzo[d]imidazole (CAS 1388070-38-9)
- (2-Fluorophenyl)diphenylmethanol (CAS 427-24-7)
- 5-Bromo-2-(2-methoxy-4-methylphenoxy)pyrimidine (CAS 1017789-03-5)
- Sodium;3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,11,11,12,12,12-henicosafluorododecane-1-sulfonate (CAS 108026-35-3)
- Semaglutide impurity 40 (CAS CATO-C4X-222640)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com