Ledipasvir impurity 37 CAS CATO-C4X-331337
| CAS No. | CATO-C4X-331337 |
| Molecular Formula | C35H32F2N6 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Ledipasvir impurity 37 (CAS CATO-C4X-331337), a pharmacopoeial impurity reference standard (molecular formula C35H32F2N6HCl, MW 611.14 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Ledipasvir impurity 37 (C35H32F2N6HCl) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C35H32F2N6 HCl |
| Molecular Weight | 611.14 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 21.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 6 |
Related Ledipasvir Standards
- Ledipasvir Impurity-3 (CAS 1256388-50-7)
- Ledipasvir (CAS 1256388-51-8)
- Ledipasvir Intermediate (CAS 1256393-27-7)
- Ledipasvir impurity 1 (CAS 134877-62-6)
- Ledipasvir Impurity 7 (CAS 1441670-89-8)
- Ledipasvir Acetone (CAS 1441674-54-9)
- Ledipasvir Impurity 8 (CAS 1499193-65-5)
- Ledipasvir D-tartrate (CAS 1502654-87-6)
Recommended Standards
- Levothyroxine Impurity 44 (CAS 176258-89-2)
- Avatrombopag Impurity 85 (CAS 677762-31-1)
- Dotinurad Impurity 171 (CAS 50910-59-3)
- (E)-N-Methyl-N-((3-methylbenzofuran-2-yl)methyl)-3-(7-oxo-5,6,7,8-tetrahydro-1,8-naphthyridin-3-yl)acrylamide (CAS 620175-39-5)
- 2-Fluoro-6-isopropoxybenzonitrile (CAS 1267631-21-9)
- 4-(3-Methyl-1,2,4-oxadiazol-5-yl)cyclohexan-1-amine (CAS 1178049-16-5)
- 2-((2,4-Dichlorophenyl)amino)-5,6-dimethylpyrimidin-4-ol (CAS 1374509-56-4)
- 2-Bromo-1-(2-hydroxybenzo[d]oxazol-4-yl)ethanone (CAS 1804085-80-0)
- (4,5-Difluoro-2-methoxyphenyl)methanol (CAS 886761-72-4)
- Semaglutide impurity 62 (CAS CATO-C4X-222662)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com