Atrasentan Impurity 1 CAS CATO-C4X-33471
| CAS No. | CATO-C4X-33471 |
| Molecular Formula | C28H38N2O6 |
| Molecular Weight | 498.61 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Atrasentan Impurity 1.
As a process- or degradation-related impurity, Atrasentan Impurity 1 (CAS CATO-C4X-33471, C28H38N2O6) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Atrasentan Impurity 1 (C28H38N2O6) contains a steroid core, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Atrasentan Impurity 1 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C28H38N2O6 |
| Molecular Weight | 498.61 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 85% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 2 |
Related Atrasentan Standards
- Atrasentan Impurity 185 (CAS CATO-C4X-3347185)
- Atrasentan Impurity 5 (CAS CATO-C4X-33475)
- Atrasentan Impurity 13 (CAS 1063836-08-7)
- Atrasentan Impurity 12 (CAS 1098784-86-1)
- Atrasentan Impurity 16 (CAS 1140617-36-2)
- Atrasentan Impurity 18 (CAS 1140617-37-3)
- Atrasentan Impurity 24 (CAS 1058395-22-4)
- Atrasentan Impurity 25 (CAS 1058395-23-5)
Recommended Standards
- Mupirocin EP Impurity C (CAS 85248-93-7)
- Mupirocin impurity 45 (CAS CATO-C4X-170645)
- 2-((4-Allyl-5-(pyridin-2-yl)-4H-1,2,4-triazol-3-yl)thio)-N-(4-(6-methylbenzo[d]thiazol-2-yl)phenyl)acetamide (CAS 573669-54-2)
- Mupirocin Impurity 21 (CAS CATO-C4X-170621)
- Allopurinol impurity 27 (CAS CATO-C4X-145827)
- Vigabatrin Impurity 12 (CAS CATO-C4X-119612)
- Imrecoxib Impurity 50 (CAS CATO-C4X-237950)
- 1-(3-Chloro-5-hydroxyphenyl)ethanone (CAS 23164-97-8)
- Methyl 1-bromo-4-methylisoquinoline-3-carboxylate (CAS 1354035-57-6)
- (2-aminophenyl)-phenylmethanone oxime 51674-05-6 A828727 N-[(2-aminophenyl)-phenyl-methylidene]hydroxylamine (CAS 51674-05-6)
- 1,4-Dihydro-6-methylquinoxaline-2,3-dione 6-Methyl-1,4-dihydroquinoxaline-2,3-dione 6-Methylquinoxaline-2,3-diol 6309-61-1 D2970 (CAS 6309-61-1)
- 1H-imidazole-2-carbonitrile hydrochloride (CAS 1392803-62-1)
- (R)-N-(1-(2-Aminoethyl)pyrrolidin-3-yl)-N-methylacetamide (CAS 1354003-90-9)
- Des-Lys16-Tirzepatide (CAS CATO-CPTD788957)
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