Talazoparib Impurity 2 CAS CATO-C4X-33732
| CAS No. | CATO-C4X-33732 |
| Molecular Formula | C19H14F2N6O |
| Molecular Weight | 380.35 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Talazoparib Impurity 2 (CAS CATO-C4X-33732) is a certified pharmaceutical impurity reference standard with the molecular formula C19H14F2N6O and a molecular weight of 380.35 g/mol.
The molecular framework of Talazoparib Impurity 2 (C19H14F2N6O) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C19H14F2N6O |
| Molecular Weight | 380.35 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 6 |
Related Talazoparib Standards
- Talazoparib Impurity N20 (CAS 1207456-00-5)
- Talazoparib (CAS 1207456-01-6)
- Talazoparib Impurity 1 (CAS CATO-C4X-33731)
- Talazoparib Impurity 7 (CAS CATO-C4X-33737)
- Talazoparib Impurity 5 (CAS CATO-C4X-33735)
- Talazoparib Impurity N57 (CAS 1425767-92-5)
- Talazoparib Impurity 3 (CAS 1322616-36-3)
- Talazoparib Impurity 8 (CAS CATO-C4X-33738)
Recommended Standards
- Fruquintinib Impurity 14 (CAS CATO-C4X-303714)
- Coumetarol (CAS 4366-18-1)
- Carbazochrome Impurity 37 (CAS CATO-C4X-229138)
- 4-Chloro-2,6-diiodophenol (CAS 15459-50-4)
- Valaciclovir EP Impurity G (CAS 1122-58-3)
- Cefminox Impurity 27 (CAS 75498-97-4)
- Palbociclib Impurity 41 (CAS CATO-C4X-112541)
- 4-Ethoxy-6,7-dimethylquinoline-2-carboxylic acid (CAS 1355196-23-4)
- 2-(Trifluoromethyl)cyclopropan-1-amine hydrochloride (CAS 1172072-62-6)
- 1-((4-Bromobenzyl)oxy)-6-nitro-2-phenyl-1H-benzo[d]imidazole (CAS 303148-89-2)
- 2,3,5,7-Tetrachloroquinoxaline (CAS 2959-05-9)
- rac-(2R,5R)-5-(thiophen-2-yl)pyrrolidine-2-carboxylic acid hydrochloride (CAS 1969288-21-8)
- 4'-Decyl-[1,1'-biphenyl]-4-carbonitrile (CAS 59454-35-2)
- Neuropeptide K, porcine (CAS 106441-70-7)
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