Talazoparib Impurity N20 CAS 1207456-00-5
| CAS No. | 1207456-00-5 |
| Molecular Formula | C19H14F2N6O |
| Molecular Weight | 380.35 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
CATO supplies Talazoparib Impurity N20 (CAS 1207456-00-5), a pharmacopoeial impurity reference standard (molecular formula C19H14F2N6O, MW 380.35 g/mol) used for the identification and quantification of trace impurities in APIs.
Structurally, Talazoparib Impurity N20 (C19H14F2N6O) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 15.0, corresponding to approximately 15 ring(s) or double-bond equivalent(s). With a molecular weight of 380.35 g/mol, it falls into the moderately-high-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C19H14F2N6O |
| Molecular Weight | 380.35 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 6 |
Related Talazoparib Standards
- Talazoparib (CAS 1207456-01-6)
- Talazoparib Impurity 2 (CAS CATO-C4X-33732)
- Talazoparib Impurity 1 (CAS CATO-C4X-33731)
- Talazoparib Impurity 7 (CAS CATO-C4X-33737)
- Talazoparib Impurity 5 (CAS CATO-C4X-33735)
- Talazoparib Impurity N57 (CAS 1425767-92-5)
- Talazoparib Impurity 3 (CAS 1322616-36-3)
- Talazoparib Impurity 8 (CAS CATO-C4X-33738)
Recommended Standards
- BMN 673 (CAS 1207454-56-5)
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- Cefpodoxime Impurity 54 (CAS CATO-C4X-157954)
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- Phenytoin Impurity N15 (CAS 2784-27-2)
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