Tivozanib Impurity 22 CAS CATO-C4X-340022
| CAS No. | CATO-C4X-340022 |
| Molecular Formula | C9H9NO5 |
| Molecular Weight | 211.17 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Tivozanib Impurity 22 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
As a process- or degradation-related impurity, Tivozanib Impurity 22 (CAS CATO-C4X-340022, C9H9NO5) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C9H9NO5, Tivozanib Impurity 22 contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 211.17 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C9H9NO5 |
| Molecular Weight | 211.17 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | ≥95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 1 |
Related Tivozanib Standards
- Tivozanib Impurity 21 (CAS CATO-C4X-340021)
- Tivozanib Impurity 27 (CAS CATO-C4X-340027)
- Tivozanib Impurity 11 (CAS CATO-C4X-340011)
- Tivozanib Impurity 3 (CAS 60144-85-6)
- Tivozanib Impurity 9 (CAS 1808274-21-6)
- Tivozanib Impurity 6 (CAS CATO-C4X-34006)
- Tivozanib Impurity 4 (CAS CATO-C4X-34004)
- Tivozanib Impurity 17 (CAS CATO-C4X-340017)
Recommended Standards
- Fruquintinib Impurity 3 (CAS 854660-58-5)
- Gentisuric Acid (CAS 25351-24-0)
- Nicorandil Impurity 52 (CAS CATO-C4X-190752)
- DIMBOA (CAS 15893-52-4)
- Parecoxib Impurity 42 (CAS CATO-C4X-159142)
- Roxatidine Impurity 59 (CAS CATO-C4X-121359)
- Pitavastatin Impurity 99 (CAS 176593-07-0)
- 6-Bromobenzo[d]thiazole-2-carboxylic acid (CAS 1187928-32-0)
- 2-Acetyl-7-fluoro-4H-quinolizin-4-one (CAS 1855081-67-2)
- (2-Bromo-5-nitrophenyl)(phenyl)methanone (CAS 183110-88-5)
- 1-[(2,3-Dihydro-1,4-benzodioxin-6-yl)sulfonyl]-4-piperidinecarboxylic acid (CAS 461456-17-7)
- Fexofenadine Impurity 42 (CAS 214601-54-4)
- 1-Ethyl-4-iodo-3-(trifluoromethyl)-1h-pyrazole (CAS 1443279-13-7)
- Semaglutide impurity 70 (CAS CATO-C4X-222670)
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