Tivozanib Impurity 23 CAS CATO-C4X-340023
| CAS No. | CATO-C4X-340023 |
| Molecular Formula | C29H26ClN3O5 |
| Molecular Weight | 531.99 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Tivozanib Impurity 23 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies Tivozanib Impurity 23 (CAS CATO-C4X-340023), a pharmacopoeial impurity reference standard (molecular formula C29H26ClN3O5, MW 531.99 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Tivozanib Impurity 23 (C29H26ClN3O5) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C29H26ClN3O5 |
| Molecular Weight | 531.99 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | ≥95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 18.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Tivozanib Standards
- Tivozanib Impurity 25 (CAS CATO-C4X-340025)
- Tivozanib Impurity 16 (CAS CATO-C4X-340016)
- Tivozanib Impurity 14 (CAS CATO-C4X-340014)
- Tivozanib Impurity 13 (CAS CATO-C4X-340013)
- Tivozanib Impurity 20 (CAS CATO-C4X-340020)
- Tivozanib Impurity 10 (CAS CATO-C4X-340010)
- Tivozanib D6 (CAS CATO-C4X-34001)
- Tivozanib (CAS 475108-18-0)
Recommended Standards
- N-Propionylbenzamide (CAS 28358-79-4)
- 2,4-Diphenyl-1,3,2,4-diselenadiphosphetane 2,4-Diselenide (CAS 122039-27-4)
- Chloro[1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene]silver (CAS 873297-19-9)
- Rupatadine EP Impurity A (CAS 1354055-68-7)
- Diclofenac Impurity 43 (CAS CATO-C4X-105143)
- Lefamulinum Impurity 45 (CAS CATO-C4X-304745)
- Terbutaline Impurity 51 (CAS 34068-01-4)
- Polyquaternium-37 (CAS 26161-33-1)
- (S)-3-(1H-Imidazol-4-yl)-2-(2-(2-mercaptoacetamido)acetamido)propanoic acid (CAS 66516-06-1)
- 2-((4-Chlorophenyl)thio)-1-(4-methyl-2-phenylthiazol-5-yl)ethan-1-one (CAS 478047-38-0)
- Methyl 3-[2-(4-methyl-2-phenyl-1,3-thiazol-5-yl)-2-oxoethoxy]-2-thiophenecarboxylate (CAS 478047-49-3)
- Vitamin K1 Impurity 67 (CAS 4444-14-8)
- 2-Amino-N-cyclohexyl-N-ethylpropanamidehydrochloride (CAS 1246172-64-4)
- D-[Thr]5-Semaglutide (CAS CATO-C4X-2226245)
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