Methazolamide Impurity 1 CAS CATO-C4X-34041
| CAS No. | CATO-C4X-34041 |
| Molecular Formula | C5H7N3O4S2 |
| Molecular Weight | 237.26 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Methazolamide Impurity 1 is closely related to a carbohydrate-derived structure, an amide group, a sulfone group in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Methazolamide Impurity 1 (CAS CATO-C4X-34041) is a certified pharmaceutical impurity reference standard with the molecular formula C5H7N3O4S2 and a molecular weight of 237.26 g/mol.
The molecular framework of Methazolamide Impurity 1 (C5H7N3O4S2) is characterized by a carbohydrate-derived structure, an amide group, a sulfone group. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Methazolamide Impurity 1 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C5H7N3O4S2 |
| Molecular Weight | 237.26 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 2 |
Related Methazolamide Standards
- Methazolamide Impurity 2 (CAS 1312679-00-7)
- Methazolamide (CAS 554-57-4)
- Methazolamide Impurity 4 (CAS CATO-C4X-34044)
- Methazolamide Impurity 4 (CAS 38583-51-6)
- Methazolamide Impurity 2 (CAS CATO-C4X-34042)
- Methazolamide Impurity 5 (CAS CATO-C4X-34045)
- Methazolamide Impurity 3 (CAS CATO-C4X-34043)
- Methazolamide Impurity 6 (CAS CATO-C4X-34046)
Recommended Standards
- Atogepant Impurity 88 (CAS CATO-C4X-328588)
- 2-Amino-5(6)-Benzoylbenzimidazole (CAS 52329-60-9)
- Moxonidine EP Impurity B (CAS 75439-01-9)
- 3-(thiophene-2-carbonyl)-3-azabicyclo[3.1.0]hexane-2-carboxylic acid (CAS 1008645-20-2)
- Rel-Mirogabalin Impurity 122 (Enantiomer Mixture) (CAS 1234045-56-7)
- Aprepitant Impurity 76 (CAS CATO-C4X-114176)
- Rocuronium Impurity 51 (CAS 103088-58-0)
- 3,4-Dichlorobenzyl isothiocyanate (CAS 18967-42-5)
- 1-(4-Methoxybenzyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole (CAS 1105039-88-0)
- 2-Fluoro-6-(trifluoromethyl)benzenesulfonyl chloride (CAS 405264-04-2)
- 4-[2-(3-bromophenoxy)ethoxy]-3-methoxybenzaldehyde (CAS 568553-39-9)
- 2-(Bromomethyl)-4-chloro-6-(difluoromethyl)-3-methoxypyridine (CAS 1805079-85-9)
- Methyl 4-(cyanomethoxy)benzoate (CAS 137988-24-0)
- Acetyl Hexapeptide-39 (CAS 1382088-38-1)
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