Dorzagliatin Impurity 13 CAS CATO-C4X-344113
| CAS No. | CATO-C4X-344113 |
| Molecular Formula | C22H27ClN4O5 |
| Molecular Weight | 462.93 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Dorzagliatin Impurity 13 is closely related to a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Dorzagliatin Impurity 13 (CAS CATO-C4X-344113) is a certified pharmaceutical impurity reference standard with the molecular formula C22H27ClN4O5 and a molecular weight of 462.93 g/mol.
The molecular framework of Dorzagliatin Impurity 13 (C22H27ClN4O5) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Dorzagliatin Impurity 13 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C22H27ClN4O5 |
| Molecular Weight | 462.93 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | ≥95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
Related Dorzagliatin Standards
- Dorzagliatin (CAS 1191995-00-2)
- Dorzagliatin Impurity N98 (CAS 1191996-10-7)
- Dorzagliatin Impurity 14 (CAS CATO-C4X-344114)
- Dorzagliatin Impurity 5 (CAS CATO-C4X-34415)
- Dorzagliatin Impurity 6 (CAS CATO-C4X-34416)
- Dorzagliatin Impurity 15 (CAS CATO-C4X-344115)
- Dorzagliatin Impurity 11 (CAS 1191996-09-4)
- Dorzagliatin Impurity 4 (CAS CATO-C4X-34414)
Recommended Standards
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- 3-Benzyl-5-[(1E)-{[(3-chlorophenyl)methoxy]imino}methyl]-4-hydroxy-1-[2-(1H-imidazol-4-yl)ethyl]-1,2-dihydropyridin-2-one (CAS 477888-15-6)
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- 5-Isopropoxy-2-methylbenzoic acid (CAS 1266965-23-4)
- 2-((1H-Benzo[d]imidazol-2-yl)methyl)oxazole (CAS 40609-32-3)
- Ethyl 2-(3-aminophenyl)oxazole-4-carboxylate (CAS 885274-73-7)
- Methyl 3-(methyl(3-methylbutan-2-yl)amino)propanoate (CAS 1156402-32-2)
- 3-Chloro-1-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)dibenzofuran (CAS 2404594-48-3)
- N-(4,5-Dihydro-1H-imidazol-2-yl)benzo[d]thiazol-6-amine (CAS 196204-80-5)
- Semaglutide Impurity 148 (CAS CATO-C4X-2226148)
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