Brensocatib Impurity 2 CAS CATO-C4X-35222
| CAS No. | CATO-C4X-35222 |
| Molecular Formula | C23H23N5O5 |
| Molecular Weight | 449.46 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Brensocatib Impurity 2.
As a process- or degradation-related impurity, Brensocatib Impurity 2 (CAS CATO-C4X-35222, C23H23N5O5) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Brensocatib Impurity 2 (C23H23N5O5) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C23H23N5O5 |
| Molecular Weight | 449.46 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 5 |
Related Brensocatib Standards
Recommended Standards
- Aztreonam Methyl Ester (CAS CATO-C4X-152216)
- 4-Bromo-6-chloro-2-(3-iodophenyl)-2H-benzo[d][1,2,3]triazol-5-amine (CAS 1706444-50-9)
- Aztreonam impurity 109 (CAS CATO-C4X-1522109)
- 1-[(4-Aminobenzyl)thio]cellobiose (CAS 68636-49-7)
- Teneligliptin Impurity 55 (CAS CATO-C4X-176055)
- Baricitinib Impurity 31 (CAS 335654-06-3)
- Venetoclax Impurity 137 (CAS CATO-C4X-2495137)
- 4-Bromo-1-methyl-1H-pyrrolo[3,2-c]pyridine (CAS 1369356-33-1)
- Naloxone impurity 14 (CAS CATO-C4X-149314)
- Mitoxantrone-d (CAS 1189974-82-0)
- Olmesartan Impurity 105 (CAS CATO-C4X-1097105)
- 4-Propyl-4H-1,2,4-triazole-3-carbaldehyde (CAS 497855-55-7)
- 5-Bromo-2-fluoro-3-methylaniline (CAS 1393442-46-0)
- Glu17-Semaglutide (CAS CATO-C4X-2226209)
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