Baricitinib Impurity 31 CAS 335654-06-3
| CAS No. | 335654-06-3 |
| Molecular Formula | C6H4ClN3 |
| Molecular Weight | 153.57 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Baricitinib Impurity 31.
CATO supplies Baricitinib Impurity 31 (CAS 335654-06-3), a pharmacopoeial impurity reference standard (molecular formula C6H4ClN3, MW 153.57 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C6H4ClN3, Baricitinib Impurity 31 contains a nitrile group, chlorine substitution, an aromatic ring system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 153.57 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Baricitinib Impurity 31 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C6H4ClN3 |
| Molecular Weight | 153.57 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | >90% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Baricitinib Standards
- Baricitinib Impurity N3 (CAS 136823-41-1)
- Baricitinib Impurity 22 (CAS 2075-45-8)
- Baricitinib Impurity 95 (CAS 1309430-77-0)
- Baricitinib Impurity 43 (CAS 1401222-91-0)
- Baricitinib Impurity 76 (CAS CATO-C4X-226076)
- Baricitinib Impurity 131 (CAS 90971-86-1)
- Baricitinib Impurity 133 (CAS CATO-C4X-2260133)
- Baricitinib Impurity 16 (CAS 24566-95-8)
Recommended Standards
- Roxatidine Impurity 57 (CAS 615-18-9)
- 5-Chlorobenzotriazole (CAS 94-97-3)
- Tofacitinib Impurity 55 (CAS 3680-69-1)
- 6-chloro-2-fluoro-pyridin-3-ol (CAS 883107-68-4)
- Ketoconazole impurity 27 (CAS CATO-C4X-147227)
- Labetalol Impurity 70 (CAS CATO-C4X-246670)
- Ethacridine Lactate Impurity 9 (CAS 38246-95-6)
- 4-bromo-3-(bromomethyl)-7-chloro-isoquinoline (CAS 2073126-58-4)
- 2-(2-Cyclopropyl-1h-benzo[d]imidazol-1-yl)acetic acid (CAS 97968-85-9)
- 2-(3-Chlorophenoxy)-5-fluoroaniline (CAS 946716-93-4)
- 3-Amino-1-(2,2-diethoxyethyl)pyridin-2(1H)-one (CAS 2171110-38-4)
- 3,5-Bisbenzyloxybenzaldehyde, 97% (CAS 14615-72-6)
- n-(4-Bromophenyl)butyramide (CAS 119199-11-0)
- Glucagon Monohydrochloride (CAS 28270-04-4)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com