4-[5-(3,5-Dichloro-4-fluorophenyl)-5-(trifluoromethyl)-4,5-dihydro-1,2-oxazol-3-yl]-N-hydroxy-2-methylbenzamide CAS CATO-CCPD103645
| CAS No. | CATO-CCPD103645 |
| Molecular Formula | C18H12Cl2F4N2O3 |
| Molecular Weight | 451.20 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
4-[5-(3,5-Dichloro-4-fluorophenyl)-5-(trifluoromethyl)-4,5-dihydro-1,2-oxazol-3-yl]-N-hydroxy-2-methylbenzamide (C18H12Cl2F4N2O3) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
4-[5-(3,5-Dichloro-4-fluorophenyl)-5-(trifluoromethyl)-4,5-dihydro-1,2-oxazol-3-yl]-N-hydroxy-2-methylbenzamide (CAS CATO-CCPD103645), molecular formula C18H12Cl2F4N2O3 and molecular weight 451.20 g/mol, is a CATO reference standard with documented purity and traceability.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 4-[5-(3,5-Dichloro-4-fluorophenyl)-5-(trifluoromethyl)-4,5-dihydro-1,2-oxazol-3-yl]-N-hydroxy-2-methylbenzamide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C18H12Cl2F4N2O3 |
| Molecular Weight | 451.20 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related Dichloro Standards
- 1-(2,4-Dichloro-5-(2-methoxyethoxy)phenyl)-N-(2-methoxyphenyl)-5-methyl-1H-1,2,4-triazole-3-carboxamide (CAS 400088-24-6)
- 2-[6,7-Dichloro-3-(trifluoromethyl)quinoxalin-2-yl]-2-(2,4-dichlorophenyl)acetonitrile (CAS 478046-34-3)
- (E)-2,4-dichloro-N'-(4-((2-chloro-6-fluorobenzyl)oxy)benzylidene)benzohydrazide (CAS 477862-47-8)
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- 5,7-Dichloro-4-(2,4,5-trichlorophenoxy)-2-(trifluoromethyl)-1H-benzo[d]imidazole (CAS 63405-99-2)
- 3-(1-(2,6-Dichloro-3-fluorophenyl)ethoxy)-5-(1-(piperidin-4-yl)-1H-pyrazol-4-yl)pyridin-2-amine (CAS 877400-66-3)
- (3E)-3-{2-[2,6-dichloro-4-(trifluoromethyl)phenyl]hydrazin-1-ylidene}-1-phenyl-2,3-dihydro-1H-indol-2-one (CAS 303984-84-1)
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Recommended Standards
- 3,7-Bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-10H-phenothiazine (CAS 1453809-16-9)
- Resmetirom impurity 132 (CAS 2542038-65-1)
- 6-(2,6-Dichlorobenzyl)-2-(3,4-dichlorophenyl)-5,7-dimethylpyrazolo[1,5-a]pyrimidine (CAS 477858-94-9)
- Resmetirom Impurity 26 (CAS 2222607-69-2)
- N-Methyl-4-(trifluoromethoxy)benzamide (CAS 60034-88-0)
- 4,4'-(1,3,6,8-Tetraoxo-1,3,6,8-tetrahydrobenzo[lmn][3,8]phenanthroline-2,7-diyl)dibenzoic acid (CAS 49546-06-7)
- Ethyl 7-(diethylamino)-2-oxo-2H-chromene-3-carboxylate (CAS 28705-46-6)
- (E)-(1,2-Diphenylhex-1-en-1-yl)boronic acid (CAS 918793-64-3)
- Methyl 6-Bromopyridine-2-carboxylate (CAS 26218-75-7)
- Methyl 6-(((3-butyl-5-methylisoxazol-4-yl)methyl)amino)nicotinate (CAS 1254962-95-2)
- Methyl N-(4-isopropylphenyl)-N-(phenylsulfonyl)glycinate (CAS 331750-13-1)
- 1,2,3-Tri-13(Z),16(Z)-Docosadienoyl-glycerol (CAS 958760-53-7)
- 1-(pyrrolidin-3-yl)-1H-1,2,3-triazole dihydrochloride 1955557-41-1 Z2465619836 (CAS 1955557-41-1)
- Endo-Ala35-Tirzepatide (CAS CATO-CPTD788687)
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