Amorolfine EP Impurity O HCI CAS CATO-CP145986
| CAS No. | CATO-CP145986 |
| Molecular Formula | C19H31NO |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Amorolfine EP Impurity O HCI (CAS CATO-CP145986, C19H31NOHCl) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Amorolfine EP Impurity O HCI (C19H31NOHCl) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C19H31NO HCl |
| Molecular Weight | 325.92 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Amorolfine Standards
- Amorolfine EP Impurity F (CAS 106614-66-8)
- Amorolfine Hydrochloride - Impurity G (CAS 1260498-34-7)
- Amorolfine EP Impurity G HCl (CAS 1260498-35-8)
- Amorolfine EP Impurity B (CAS 142347-84-0)
- Amorolfine Impurity 87 (CAS 1688675-10-6)
- Amorolfine Impurity 89 (CAS 1689944-83-9)
- Amorolfine Impurity 62 (CAS 1800302-57-1)
- trans-Amorolfine (CAS 2134097-34-8)
Recommended Standards
- Pethidine impurity 6 (CAS CATO-C4X-22326)
- Apalutamide Impurity 33 (CAS CATO-C4X-274933)
- Olmesartan Impurity 87 (CAS CATO-C4X-109787)
- 2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(4-methylthiazol-2-yl)propanoic acid (CAS 1379844-17-3)
- 2-[(5-cyano-2,3'-bipyridin-6-yl)thio]propanoic acid (CAS 445391-28-6)
- Octahydro-1H-quinolizine-3-carbonitrile (CAS 73259-83-3)
- 6-Amino-4,5-dichloro-2-methylpyridazin-3(2H)-one (CAS 25717-64-0)
- Ethyl 4-oxo-4H-chromene-6-carboxylate (CAS 67733-31-7)
- 2-Chloro-1H-naphtho[2,3-d]imidazole (CAS 71670-67-2)
- Peptide Impurity 82 (CAS 10491-78-8)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com