Valsartan Impurity 76 CAS CATO-C4X-105776
| CAS No. | CATO-C4X-105776 |
| Molecular Formula | C25H31N5O3 |
| Molecular Weight | 449.55 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Valsartan Impurity 76 is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Valsartan Impurity 76 (CAS CATO-C4X-105776) is a certified pharmaceutical impurity reference standard with the molecular formula C25H31N5O3 and a molecular weight of 449.55 g/mol.
Valsartan Impurity 76 (C25H31N5O3) contains a steroid core, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Valsartan Impurity 76 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C25H31N5O3 |
| Molecular Weight | 449.55 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 5 |
Related Valsartan Standards
- Valsartan Impurity 106 (CAS CATO-C4X-1057106)
- Valsartan Impurity 112 (CAS CATO-C4X-1057112)
- Valsartan Impurity 120 (CAS 137863-48-0)
- Valsartan Impurity 125 (CAS 1894176-40-9)
- Valsartan USP Related Compound E (CAS 137863-17-3)
- Valsartan Impurity 73 (CAS CATO-C4X-105773)
- Valsartan Impurity 74 (CAS CATO-C4X-105774)
- Valsartan Impurity 75 (CAS CATO-C4X-105775)
Recommended Standards
- Valsartan Impurity 77 (CAS CATO-C4X-105777)
- Valsartan Impurity 78 (CAS CATO-C4X-105778)
- Valsartan Impurity 8 (CAS 137862-78-3)
- Valsartan Impurity 83 (CAS CATO-C4X-105783)
- Melphalan Impurity 38 (CAS CATO-C4X-198838)
- Afatinib Impurity 58 (CAS CATO-C4X-100658)
- Bumetanide Impurity 107 (CAS CATO-C4X-1986107)
- Methyl 6-methoxy-1H-benzo[d]imidazole-7-carboxylate (CAS 1193789-02-4)
- 2-cyclobutanecarbonyloxolane (CAS 1600972-63-1)
- N-(2-Hydroxyethyl)-4-propoxynaphthalene-1-sulfonamide (CAS 1206105-01-2)
- 5-(1-Methyl-1h-pyrazol-5-yl)-1,3,4-thiadiazol-2-amine (CAS 1342779-21-8)
- Benzyl pyrrolidine-2-carboxylate (CAS 80089-25-4)
- Floxuridine Impurity 1 (CAS 3094-09-0)
- Semaglutide impurity 88 (CAS CATO-C4X-222688)
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