Safinamide Impurity 16 CAS 1000370-24-0
| CAS No. | 1000370-24-0 |
| Molecular Formula | C21H16F2O2 |
| Molecular Weight | 338.35 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO supplies Safinamide Impurity 16 (CAS 1000370-24-0), a pharmacopoeial impurity reference standard (molecular formula C21H16F2O2, MW 338.35 g/mol) used for the identification and quantification of trace impurities in APIs.
Structurally, Safinamide Impurity 16 (C21H16F2O2) contains a steroid core, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 13.0, corresponding to approximately 13 ring(s) or double-bond equivalent(s). With a molecular weight of 338.35 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a certified reference material (CRM), Safinamide Impurity 16 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C21H16F2O2 |
| Molecular Weight | 338.35 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | F-containing |
Related Safinamide Standards
- Safinamide Impurity 68 (CAS CATO-C4X-159068)
- Safinamide Impurity 62 (CAS CATO-C4X-159062)
- Safinamide Impurity 3 (CAS CATO-C4X-15903)
- Safinamide Impurity 38 (CAS 1827614-91-4)
- Safinamide Impurity 34 (CAS CATO-C4X-159034)
- Safinamide Impurity 4 (CAS CATO-C4X-15904)
- Safinamide Impurity 46 (CAS 2268802-59-9)
- Safinamide Impurity 2 (CAS 1160513-60-9)
Recommended Standards
- Mycophenolate Impurity 26 (CAS CATO-C4X-151526)
- Fluralaner Impurity 18 (CAS CATO-C4X-218018)
- Mycophenolate Impurity 25 (CAS CATO-C4X-151525)
- Fluralaner Impurity 48 (CAS CATO-C4X-218048)
- Enzalutamide Impurity N1 (CAS 2227589-23-1)
- Bimatoprost Impurity 26 (CAS CATO-C4X-196426)
- Avibactam Impurity 22 (CAS 1174020-25-7)
- 1-(3-Bromobenzyl)pyrrolidin-3-ol (CAS 1044766-83-7)
- 4-(Pyridin-2-ylmethyl)oxan-4-amine dihydrochloride (CAS 1393330-59-0)
- 4-imidazolone-5-propanoate (CAS 17340-16-8)
- (E)-2-(3-Methoxystyryl)benzoic acid (CAS 81428-84-4)
- Ketoprofen-13C-d3 (CAS 1189508-77-7)
- Tert-butyl (6Z)-6-[(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)methylene]-2-azaspiro[3.4]octane-2-carboxylate (CAS 2763648-54-8)
- Semaglutide impurity 24 (CAS CATO-C4X-222624)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com