5,7-Dichloro-N-(3,5-dimethylphenyl)thiazolo[4,5-d]pyrimidine-2-sulfonamide CAS 1000573-22-7
| CAS No. | 1000573-22-7 |
| Molecular Formula | C13H10Cl2N4O2S2 |
| Molecular Weight | 389.28 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 5,7-Dichloro-N-(3,5-dimethylphenyl)thiazolo[4,5-d]pyrimidine-2-sulfonamide is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
5,7-Dichloro-N-(3,5-dimethylphenyl)thiazolo[4,5-d]pyrimidine-2-sulfonamide (CAS 1000573-22-7), molecular formula C13H10Cl2N4O2S2 and molecular weight 389.28 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution, 5,7-Dichloro-N-(3,5-dimethylphenyl)thiazolo[4,5-d]pyrimidine-2-sulfonamide is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 389.28 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 5,7-Dichloro-N-(3,5-dimethylphenyl)thiazolo[4,5-d]pyrimidine-2-sulfonamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C13H10Cl2N4O2S2 |
| Molecular Weight | 389.28 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 2 |
Related Dichloro Standards
- 5,7-Dichloro-N-(2,4-dimethylphenyl)thiazolo[4,5-d]pyrimidine-2-sulfonamide (CAS 1000573-16-9)
- 5,7-Dichloro-N-(3,4-dimethylphenyl)thiazolo[4,5-d]pyrimidine-2-sulfonamide (CAS 1000573-28-3)
- 5,7-Dichloro-N-ethyl-N-phenylthiazolo[4,5-d]pyrimidine-2-sulfonamide (CAS 1000573-46-5)
- 5,7-Dichloro-N-methyl-N-(o-tolyl)thiazolo[4,5-d]pyrimidine-2-sulfonamide (CAS 1000576-49-7)
- 26379-96-4 Ethyl 1~4~,3~4~-dichloro-2~5~-oxo-2~2~,2~3~,2~4~,2~5~-tetrahydro[1~1~,2~1~:2~3~,3~1~-terphenyl]-2~4~-carboxylate DTXSID40376897 (CAS 26379-96-4)
- {3-[(3,4-Dichloro-phenylcarbamoyl)-methyl]-4-oxo-thiazolidin-2-ylidene}-acetic acid ethyl ester (CAS 729574-24-7)
- N-(2,6-Dichloro-4-nitrophenyl)-4-methanesulfonylbenzamide (CAS 949980-68-1)
- 2,6-Dichloro-9-(3,5-di-O-acetyl-2-deoxy-α-D-erythro-pentofuranosyl)-9H-purine (CAS 4594-53-0)
Recommended Standards
- Perfluorophenyl 6-((tetrahydro-2H-pyran-4-yl)oxy)nicotinate (CAS 910036-96-3)
- 4-Chloro-2-[(4-chlorophenyl)methyl]-5-(4-fluorophenyl)thieno[2,3-d]pyrimidine (CAS 867329-94-0)
- 4-Chloro-6-{4-[5-(4-chlorophenyl)-1H-pyrazol-3-yl]piperidin-1-yl}pyrimidin-2-amine (CAS 1027619-77-7)
- 4-((5-Bromo-2-hydroxybenzylidene)amino)-3-(m-tolyl)-1H-1,2,4-triazole-5(4H)-thione (CAS 478255-73-1)
- 3-(4-Pyridin-2-yl-thiazol-2-ylamino)benzoic acid 3-(4-pyridin-2-yl-thiazol-2-ylamino)-benzoic acid 3-(4-pyridin-2-ylthiazol-2-ylamino)benzoic acid 315702-87-5 (CAS 315702-87-5)
- 3-((3-Chlorobenzyl)thio)-4-ethyl-5-(furan-2-yl)-4H-1,2,4-triazole (CAS 618413-51-7)
- 4-(2-chlorophenyl)butanenitrile (CAS 91552-19-1)
- 1-Benzyl-4-[(4-methoxyphenyl)sulfanyl]phthalazine (CAS 338978-21-5)
- (R)-1-(2,6-dichlorophenyl)-2-methoxyethan-1-amine (CAS 1270081-72-5)
- 2,4-Difluoro-3-methoxybenzaldehyde (CAS 870837-66-4)
- 1707357-83-2 2-Nitro-6-(thiazolidin-3-yl)benzaldehyde (CAS 1707357-83-2)
- 8-Amino-2,3-dimethylquinoxaline-6-carboxylic acid (CAS 1706434-89-0)
- 2-Bromo-4-chloro-6-nitroaniline (CAS 827-25-8)
- Tau Peptide (273-284) trifluoroacetate salt (CAS 1663490-91-2)
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