Rizatriptan EP Impurity I CAS 144034-84-4
| CAS No. | 144034-84-4 |
| Molecular Formula | C14H17N5 |
| Molecular Weight | 255.32 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 255.32 g/mol gives Rizatriptan EP Impurity I distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies Rizatriptan EP Impurity I (CAS 144034-84-4), a pharmacopoeial impurity reference standard (molecular formula C14H17N5, MW 255.32 g/mol) used for the identification and quantification of trace impurities in APIs.
Structurally, Rizatriptan EP Impurity I (C14H17N5) contains a nitrogen-containing heterocyclic scaffold, a nitrile group. The molecule exhibits a degree of unsaturation (DBE) of 9.0, corresponding to approximately 9 ring(s) or double-bond equivalent(s). With a molecular weight of 255.32 g/mol, it falls into the medium-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Rizatriptan EP Impurity I meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C14H17N5 |
| Molecular Weight | 255.32 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1998 |
| Nitrogen Atoms | 5 |
Related Rizatriptan Standards
- Rizatriptan Impurity 6 (CAS 177270-91-6)
- Rizatriptan EP Impurity G (CAS 1000673-59-5)
- Rizatriptan Impurity 14 (CAS 4454-01-7)
- Rizatriptan EP Impurity F (CAS 160194-39-8)
- Rizatriptan Impurity N8 (CAS 1034806-43-3)
- Rizatriptan - API Standards (CAS 144034-80-0)
- Rizatriptan EP Impurity C (CAS 208941-96-2)
- Rizatriptan-D6 (CAS 606927-07-5)
Recommended Standards
- (2-Methyl-6-pyrrolidin-2-yl-pyridin-4-yl)-pyrazin-2-yl-amine (CAS 1361118-52-6)
- 3-Amino-n-(thiazol-2-yl)benzenesulfonamide (CAS 146374-23-4)
- N-(2-methyl-6-(pyrrolidin-3-yl)pyridin-4-yl)pyrimidin-2-amine (CAS 1361114-81-9)
- 8-Amino-7-chloro-[1,2,4]triazolo[1,5-c]pyrimidin-2(3H)-one (CAS 15129-01-8)
- Trazodone Impurity 29 (CAS 2727463-29-6)
- Atracurium Impurity 32 (CAS CATO-C4X-185032)
- Daprodustat Impurity 15 (CAS 65461-92-9)
- 4-Bromo-1,3-dihydro-5-methyl-2H-benzimidazol-2-one (CAS 1388043-57-9)
- (2S,4R)-6-Chloro-4-hydroxychroman-2-carboxylic acid (CAS 2529546-35-6)
- 2-[5-methyl-1-(4-methylphenyl)-1h-1,2,3-triazol-4-yl]acetic acid (CAS 1017423-18-5)
- [(5-bromothiophen-2-yl)methyl](ethyl)amine (CAS 851788-23-3)
- 3-aminonaphthalene-2-carbonitrile (CAS 27533-39-7)
- 5-(1-Phenyl-1H-pyrrol-2-yl)pyridazine-4-carbonitrile (CAS 919785-70-9)
- D-Gln24-Tirzepatide (CAS CATO-CPTD788910)
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