Pemetrexed Impurity 21 CAS 1001-19-0
| CAS No. | 1001-19-0 |
| Molecular Formula | C9H17NO4 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Pemetrexed Impurity 21 (CAS 1001-19-0), a pharmacopoeial impurity reference standard (molecular formula C9H17NO4HCl, MW 239.70 g/mol) used for the identification and quantification of trace impurities in APIs.
Pemetrexed Impurity 21 (C9H17NO4HCl) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Pemetrexed Impurity 21 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H17NO4 HCl |
| Molecular Weight | 239.70 g/mol |
| Purity | >90% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 1.0 |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Pemetrexed Standards
- Pemetrexed Impurity 11 (CAS 100643-27-4)
- Pemetrexed Impurity 22 (CAS 1075-59-8)
- Pemetrexed Impurity 54 (CAS 1265908-58-4)
- Pemetrexed EP Impurity D Trisodium salt (CAS 1265908-59-5)
- Pemetrexed Impurity (CAS 1265908-60-8)
- Pemetrexed Impurity (CAS 1265908-61-9)
- Pemetrexed Impurity 53 (CAS 1320346-37-9)
- Pemetrexed Impurity 34 (CAS 1320346-43-7)
Recommended Standards
- Ceftiofur Impurity 12 (CAS CATO-C4X-158112)
- Rivaroxaban Impurity 136 (CAS 36157-42-3)
- Dexmedetomidine Impurity 65 (CAS CATO-C4X-123065)
- 4-benzyl-6-bromo-1,4-oxazepane (CAS 1934832-28-6)
- DDMAB (CAS 15163-30-1)
- 2-sec-butylpiperidine (CAS 383128-18-5)
- 6-Amino-3-bromo-5-nitropyridin-2(1H)-one (CAS 1935346-20-5)
- 653584-64-6 A835086 N-[4-(hydroxymethyl)-3-pyridinyl]-2,2-dimethylpropanamide N-[4-(hydroxymethyl)pyridin-3-yl]-2,2-dimethyl-propanamide (CAS 653584-64-6)
- Promethazine Impurity 52 (CAS CATO-C4X-141852)
- [D-Phe22]Semaglutide (CAS CATO-C4X-2226222)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com