Dapoxetine Impurity 74 CAS 100306-33-0
| CAS No. | 100306-33-0 |
| Molecular Formula | C9H11ClO |
| Molecular Weight | 170.64 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Dapoxetine Impurity 74 is closely related to a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies Dapoxetine Impurity 74 (CAS 100306-33-0), a pharmacopoeial impurity reference standard (molecular formula C9H11ClO, MW 170.64 g/mol) used for the identification and quantification of trace impurities in APIs.
Dapoxetine Impurity 74 (C9H11ClO) contains a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C9H11ClO |
| Molecular Weight | 170.64 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | Cl-containing |
Related Dapoxetine Standards
- Dapoxetine Impurity 37 (CAS 100306-34-1)
- Dapoxetine Impurity 36 (CAS 86-56-6)
- Dapoxetine Impurity 78 (CAS 17733-68-5)
- Dapoxetine Impurity 16 (CAS 69888-75-1)
- Dapoxetine Impurity 98 (CAS CATO-C4X-143998)
- Dapoxetine Impurity 38 (CAS 40856-44-8)
- Dapoxetine Impurity 39 (CAS 13921-90-9)
- Dapoxetine Impurity 12 (CAS 3330-05-0)
Recommended Standards
- (6-chloropyridine - 3-methyl) amino ethane (CAS 120739-77-7)
- Fluoxetine Impurity 27 (CAS 18776-12-0)
- Orforglipron Impurity 43 (CAS 2025595-61-1(free base))
- Umeclidinium impurity 22 (CAS 17229-17-3)
- Toremifene impurity 5 (CAS 89778-23-4)
- Fudosteine impurity 78 (CAS CATO-C4X-144778)
- Atorvastatin Impurity 79 (CAS CATO-C4X-113279)
- 4-(3-Chloro-4-methylphenyl)benzonitrile (CAS 1352318-49-0)
- Diethyl 2-fluoro-2-(((methylsulfonyl)oxy)methyl)malonate (CAS 2710-86-3)
- spiro[cyclopropane-2,1-indane]-1-carboxylic acid (CAS 1250150-08-3)
- (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)(methyl)amino)-2-cyclohexylacetic acid (CAS 925240-97-7)
- 1-(3-Chlorophenyl)prop-2-en-1-amine (CAS 1260831-38-6)
- Ethyl 2-(pyrazin-2-ylthio)propanoate (CAS 866042-21-9)
- [3,5 Diiodo-Tyr7] Peptide T (CAS 128551-40-6)
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