4-Hydroxy-5-isopropyl-6-methyl-2-oxo-1,2-dihydro-pyridine-3-carboxylic acid ethyl ester CAS 100371-18-4
| CAS No. | 100371-18-4 |
| Molecular Formula | C12H17NO4 |
| Molecular Weight | 239.27 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
4-Hydroxy-5-isopropyl-6-methyl-2-oxo-1,2-dihydro-pyridine-3-carboxylic acid ethyl ester (CAS 100371-18-4) is a high-purity analytical reference standard with the molecular formula C12H17NO4 and a molecular weight of 239.27 g/mol.
The molecular framework of 4-Hydroxy-5-isopropyl-6-methyl-2-oxo-1,2-dihydro-pyridine-3-carboxylic acid ethyl ester (C12H17NO4) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 4-Hydroxy-5-isopropyl-6-methyl-2-oxo-1,2-dihydro-pyridine-3-carboxylic acid ethyl ester meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H17NO4 |
| Molecular Weight | 239.27 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Nitrogen Atoms | 1 |
Related Hydroxy Standards
- Ethyl 4-hydroxy-6-methyl-2-oxo-5-propyl-1,2-dihydropyridine-3-carboxylate (CAS 100371-19-5)
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- 2-Benzyl-3-hydroxy-2,3-dihydro-1H-isoindol-1-one (CAS 17448-14-5)
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Recommended Standards
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- 8-(Difluoromethoxy)-1,2,3,5,6,7-hexahydro-s-indacen-4-amine (CAS 2271392-88-0)
- 1-(Azetidin-3-yl)piperazine hydrochloride (CAS 2007920-52-5)
- Droserone (CAS 478-40-0)
- 1-(Prop-2-yn-1-yl)-1h-1,2,4-triazole (CAS 82418-39-1)
- 2,6-Dichloropyridine-4-carbothioamide (CAS 175204-46-3)
- 6-Methyl-4-(trifluoromethyl)-2,6-dihydropyrazolo[3,4-c]pyrazol-3-amine (CAS 478047-15-3)
- 1-Benzyl 3-methyl (R)-piperazine-1,3-dicarboxylate (CAS 405175-79-3)
- 2-Chloro-4-(methylsulfonyl)phenol (CAS 20945-65-7)
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- 1-(2-Cyclopropylpyrazolo[1,5-a]pyrazin-4-yl)piperidine-3-carboxylic acid (CAS 1707399-45-8)
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