Sildenafil Impurity N6 CAS 1004455-71-3
| CAS No. | 1004455-71-3 |
| Molecular Formula | C9H13N3O4 |
| Molecular Weight | 227.22 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Sildenafil Impurity N6 (C9H13N3O4) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Sildenafil Impurity N6 (CAS 1004455-71-3) is a certified pharmaceutical impurity reference standard with the molecular formula C9H13N3O4 and a molecular weight of 227.22 g/mol.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Sildenafil Impurity N6 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C9H13N3O4 |
| Molecular Weight | 227.22 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Nitrogen Atoms | 3 |
Related Sildenafil Standards
- Sildenafil Impurity N1 (CAS 911715-34-9)
- Sildenafil Impurity 34 (CAS CATO-C4X-112834)
- Sildenafil Impurity 247 (CAS 360068-47-9)
- Sildenafil Impurity N5 (CAS 60531-34-2)
- Sildenafil Impurity 76 (CAS 97-05-2)
- Sildenafil Impurity SM2 (CAS 202066-14-6)
- Sildenafil RC 41 (CAS 222729-55-7)
- Sildenafil Impurity 36 (CAS 139756-00-6)
Recommended Standards
- Ethyl-d5 beta-D-glucuronide (CAS 1135070-98-2)
- 4-(2-Fluorophenoxymethyl)benzonitrile (CAS 1016780-76-9)
- 2＇-Deoxycytidine (CAS 951-77-9)
- 3-(3-Fluorophenoxymethyl)benzonitrile (CAS 1019437-40-1)
- Loperamide impurity 13 (CAS 37742-98-6)
- Cefotaxime Impurity 50 (CAS CATO-C4X-120157)
- Chlorhexidine EP Impurity A Hydrochloride (CAS 152504-08-0（free base）)
- 4-Cyano-6-iodopyridine-2-sulfonyl chloride (CAS 1393558-41-2)
- N-Nitroso Flecainide EP Impurity B (CAS CATO-C4X-25466)
- Letermovir Impurity 32 (CAS 2994645-03-1)
- Hexadecyl decanoate (CAS 29710-34-7)
- 1-(1-Methyl-1H-pyrazol-4-yl)-N-((tetrahydro-2H-pyran-4-yl)methyl)methanamine (CAS 1341090-30-9)
- 3-(((4-Chlorobenzyl)thio)methyl)-5-((3,4-dichlorobenzyl)thio)-4-phenyl-4H-1,2,4-triazole (CAS 344273-49-0)
- Tirzepatide Impurity 44 (CAS CATO-C4X-324044)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com