Aceclofenac Benzyl Ester (Aceclofenac EP Impurity F) CAS 100499-89-6
| CAS No. | 100499-89-6 |
| Molecular Formula | C23H19Cl2NO4 |
| Molecular Weight | 444.31 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Aceclofenac Benzyl Ester (Aceclofenac EP Impurity F).
As a process- or degradation-related impurity, Aceclofenac Benzyl Ester (Aceclofenac EP Impurity F) (CAS 100499-89-6, C23H19Cl2NO4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Aceclofenac Benzyl Ester (Aceclofenac EP Impurity F) (C23H19Cl2NO4) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Aceclofenac Benzyl Ester (Aceclofenac EP Impurity F) under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C23H19Cl2NO4 |
| Molecular Weight | 444.31 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Aceclofenac Standards
- Aceclofenac Impurity 15 (CAS CATO-C4X-153115)
- Aceclofenac Impurity 14 (CAS CATO-C4X-153114)
- Aceclofenac Impurity 13 (CAS CATO-C4X-153113)
- Aceclofenac Impurity 16 (CAS CATO-C4X-153116)
- Aceclofenac Impurity 18 (CAS 2518198-70-2)
- Aceclofenac EP Impurity H (CAS 1216495-92-9)
- Aceclofenac EP Impurity G (CAS 1215709-75-3)
- Aceclofenac tert-Butyl Ester (CAS 139272-68-7)
Recommended Standards
- Bis(3-aminophenyl)(3,5-bis(trifluoromethyl)phenyl)phosphineoxide (CAS 299176-31-1)
- 1020252-71-4 4-bromo-5-({2-[(1E)-1-(ethoxyimino)ethyl]phenoxy}methyl)-1-methyl-2-phenyl-2,3-dihydro-1H-pyrazol-3-one MS-6598 (CAS 1020252-71-4)
- 2-Iodo-9,9-diphenyl-9H-fluorene (CAS 768398-90-9)
- (Perfluoropropane-2,2-diyl)bis(4,1-phenylene) diacrylate (CAS 108050-41-5)
- Olanzapine Impurity 13 (CAS CATO-C4X-117813)
- Ornidazole Impurity 72 (CAS 2643942-29-2)
- Terbutaline Impurity 37 (CAS 28917-43-3)
- (2-methoxy-6-methylpyridin-3-yl)boronic acid (CAS 1000802-75-4)
- Potassium 1H-indol-3-olate (CAS 721968-97-4)
- 1-Ethylpiperidine-4-sulfonamide (CAS 1249636-58-5)
- 5-Oxo-7a-(thiophen-2-yl)hexahydropyrrolo[2,1-b]thiazole-3-carboxylic acid (CAS 1008671-90-6)
- 1-Amino-3-(4-fluorophenyl)cyclobutane-1-carboxylic acid (CAS 1258652-54-8)
- 2-[(2,6-Dichlorophenyl)methyl]-6-phenyl-5-(piperidin-1-yl)-2,3-dihydropyridazin-3-one (CAS 478029-32-2)
- Cholecystokinin Octapeptide (1-5) (desulfated) (CAS 121880-96-4)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com