2-[(2,6-Dichlorophenyl)methyl]-6-phenyl-5-(piperidin-1-yl)-2,3-dihydropyridazin-3-one CAS 478029-32-2
| CAS No. | 478029-32-2 |
| Molecular Formula | C22H21Cl2N3O |
| Molecular Weight | 414.33 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2-[(2,6-Dichlorophenyl)methyl]-6-phenyl-5-(piperidin-1-yl)-2,3-dihydropyridazin-3-one (CAS 478029-32-2) is a high-purity analytical reference standard with the molecular formula C22H21Cl2N3O and a molecular weight of 414.33 g/mol.
The molecular framework of 2-[(2,6-Dichlorophenyl)methyl]-6-phenyl-5-(piperidin-1-yl)-2,3-dihydropyridazin-3-one (C22H21Cl2N3O) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 2-[(2,6-Dichlorophenyl)methyl]-6-phenyl-5-(piperidin-1-yl)-2,3-dihydropyridazin-3-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C22H21Cl2N3O |
| Molecular Weight | 414.33 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Dichlorophenyl Standards
- 3-(2,6-Dichlorophenyl)-N-[2-(1H-indol-3-yl)ethyl]-5-methyl-1,2-oxazole-4-carboxamide (CAS 1020252-50-9)
- 1-{6-[(2,4-dichlorophenyl)methyl]pyridazin-3-yl}-4-(4-fluorophenyl)-1H-pyrazol-5-amine (CAS 321385-80-2)
- 1-(2,4-Dichlorophenyl)-5-methyl-N-(3-(trifluoromethyl)phenyl)-1H-1,2,4-triazole-3-carboxamide (CAS 338398-20-2)
- 1-(2,5-Dichlorophenyl)-5-methyl-N-[3-(trifluoromethyl)phenyl]-1H-1,2,4-triazole-3-carboxamide (CAS 338399-11-4)
- 1-(3,5-Dichlorophenyl)-5-methyl-N-(2-(trifluoromethyl)phenyl)-1H-1,2,4-triazole-3-carboxamide (CAS 338408-92-7)
- 1-(3,5-Dichlorophenyl)-5-methyl-N-(3-(trifluoromethyl)phenyl)-1H-1,2,4-triazole-3-carboxamide (CAS 338408-45-0)
- N-(2,4-dichlorophenyl)-5-methyl-1-(3-(trifluoromethyl)phenyl)-1H-1,2,4-triazole-3-carboxamide (CAS 321431-36-1)
- 5-[(2,4-dichlorophenyl)methylidene]-3-[4-(difluoromethoxy)phenyl]-2-sulfanylideneimidazolidin-4-one (CAS 723332-02-3)
Recommended Standards
- 2-(3,4-Dichlorobenzyl)-6-phenyl-5-(piperidin-1-yl)pyridazin-3(2H)-one (CAS 478029-39-9)
- 4-[(1E)-{[3-(trifluoromethyl)phenyl]imino}methyl]phenyl 4-nitrobenzoate (CAS 331461-06-4)
- 2-(2,4-Dichlorobenzyl)-6-phenyl-5-(piperidin-1-yl)pyridazin-3(2H)-one (CAS 478029-35-5)
- 4-Oxo-3-(1-phenyl-1H-pyrazol-4-yl)-2-(trifluoromethyl)-4H-chromen-7-yl acetate (CAS 303095-18-3)
- 1-(3-Nitrophenoxy)propan-2-one (CAS 18621-37-9)
- (S)-2-(4-methylmorpholin-2-yl)ethan-1-amine (CAS 1268520-31-5)
- 1-[4-(Aminomethyl)piperidin-1-yl]-2-(4-ethoxyphenyl)ethan-1-one hydrochloride (CAS 1573035-08-1)
- 2-Chloro-5-(1-ethylpiperidin-2-yl)pyridine (CAS 1306606-79-0)
- 1-(2-(Methylamino)pyrimidin-4-yl)ethanone (CAS 645419-05-2)
- (S)-N-(Piperidin-3-yl)isoquinoline-5-sulfonamide dihydrochloride (CAS 936233-07-7)
- 2,5-Dimethyl-1-phenyl-4-phosphorinanone (CAS 54877-14-4)
- Dicyclopentadienylbisphenol cyanateester (CAS 135507-71-0)
- N-((1-(2-Chloroacetyl)piperidin-3-yl)methyl)-N-ethylacetamide (CAS 1353972-95-8)
- ((Cys31,Nva34)-Neuropeptide Y (27-36))2 (CAS 172997-92-1)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com