1-(4-(1,3-Dimethyl-1H-pyrazol-4-yl)-6-(trifluoromethyl)pyrimidin-2-yl)piperidine-4-carboxylic acid CAS 1006334-19-5
| CAS No. | 1006334-19-5 |
| Molecular Formula | C16H18F3N5O2 |
| Molecular Weight | 369.34 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
1-(4-(1,3-Dimethyl-1H-pyrazol-4-yl)-6-(trifluoromethyl)pyrimidin-2-yl)piperidine-4-carboxylic acid (CAS 1006334-19-5) is a high-purity analytical reference standard with the molecular formula C16H18F3N5O2 and a molecular weight of 369.34 g/mol.
1-(4-(1,3-Dimethyl-1H-pyrazol-4-yl)-6-(trifluoromethyl)pyrimidin-2-yl)piperidine-4-carboxylic acid (C16H18F3N5O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C16H18F3N5O2 |
| Molecular Weight | 369.34 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 5 |
Related Dimethyl Standards
- 1-[4-(1,5-dimethyl-1h-pyrazol-4-yl)-6-(trifluoromethyl)pyrimidin-2-yl]piperidine-3-carboxylic acid (CAS 1006348-78-2)
- N'-(4,6-dimethyl-3-(methylsulfonyl)pyridin-2-yl)-2,6-difluoro-N'-methylbenzohydrazide (CAS 341967-39-3)
- 1-(2-(2,2-Dimethyl(3-oxaindan-4-yloxy))acetyl)-4-(2-methylphenyl)semicarbazide (CAS 1022319-72-7)
- 2-(2,5-Dimethyl-1H-indol-3-yl)-1-(4-(tetrahydrofuran-2-carbonyl)piperazin-1-yl)ethanone (CAS 1197769-65-5)
- N-(1-(5,6-dimethyl-1H-benzo[d]imidazol-2-yl)-2-phenylethyl)benzamide (CAS 338410-51-8)
- Dimethyl 6,6'-bis(chloromethyl)-[2,2'-bipyridine]-4,4'-dicarboxylate (CAS 1956377-23-3)
- Dimethyl 5-(4-chlorophenyl)-4,6-dioxotetrahydro-2H-pyrrolo[3,4-d]isoxazole-3,3(3aH)-dicarboxylate (CAS 338420-26-1)
- 3,3-Dimethyl-11-(2-naphthyl)-2,3,4,5,10,11-hexahydro-1H-dibenzo[b,e][1,4]diazepin-1-one (CAS 886644-59-3)
Recommended Standards
- 873110-62-4 2-(4-Nitrophenyl)-1H-anthra[1,2-d]imidazole-6,11-dione MFCD20265335 (CAS 873110-62-4)
- N-(3,4-Dimethoxyphenyl)-3-nitro-4-(1H-1,2,4-triazol-1-yl)benzamide (CAS 338407-92-4)
- 6,6''-Di(2H-tetrazol-5-yl)-2,2':6',2''-terpyridine (CAS 1030597-82-0)
- Dichloroabietic acid (CAS 65281-77-8)
- 4-Hydroxytoluene-d3 (CAS 108561-00-8)
- tert-Butyl ((1-((S)-2-aminopropanoyl)piperidin-2-yl)methyl)(cyclopropyl)carbamate (CAS 1354028-60-6)
- 5-(4-Methylphenyl)-1h-pyrazole-4-carboxylic acid (CAS 879996-66-4)
- 1-[(4-Aminophenyl)methyl]-N-phenyl-imidazole-4-carboxamide (CAS 1351843-58-7)
- Ethyl 2-amino-2-methyl-3-(2-methyl-1h-imidazol-1-yl)propanoate (CAS 1249762-93-3)
- 1-Acetyl-5-(nonafluorobutyl)-3-(trifluoromethyl)-1H-pyrazole (CAS 1017793-60-0)
- (E)-N-(4-(N-(3,4-dimethylisoxazol-5-yl)sulfamoyl)phenyl)-3-(p-tolyl)acrylamide (CAS 873307-21-2)
- 4-(4-(4-Fluorophenoxy)-5-methyl-1H-pyrazol-3-yl)benzene-1,3-diol (CAS 297147-95-6)
- 5-(3-Chloro-4-methoxyphenyl)furan-2-carbonitrile (CAS 124014-02-4)
- Tirzepatide Impurity 46 (CAS CATO-C4X-324046)
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