3-(3-(5-Cyclopropyl-3-(trifluoromethyl)-1h-pyrazol-1-yl)propyl)-2-thioxo-2,3-dihydroquinazolin-4(1h)-one CAS 1006345-64-7
| CAS No. | 1006345-64-7 |
| Molecular Formula | C18H17F3N4OS |
| Molecular Weight | 394.41 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
3-(3-(5-Cyclopropyl-3-(trifluoromethyl)-1h-pyrazol-1-yl)propyl)-2-thioxo-2,3-dihydroquinazolin-4(1h)-one (C18H17F3N4OS) contains a steroid core, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
3-(3-(5-Cyclopropyl-3-(trifluoromethyl)-1h-pyrazol-1-yl)propyl)-2-thioxo-2,3-dihydroquinazolin-4(1h)-one (CAS 1006345-64-7) is a high-purity analytical reference standard with the molecular formula C18H17F3N4OS and a molecular weight of 394.41 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 3-(3-(5-Cyclopropyl-3-(trifluoromethyl)-1h-pyrazol-1-yl)propyl)-2-thioxo-2,3-dihydroquinazolin-4(1h)-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C18H17F3N4OS |
| Molecular Weight | 394.41 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
Related Cyclopropyl Standards
- 5-(N-Cyclopropyl-N-(furan-2-ylmethyl)sulfamoyl)-N-(thiazol-2-yl)furan-2-carboxamide (CAS 1172704-71-0)
- Methyl 3-cyclopropyl-1-(4-fluorophenyl)-6-(thiophen-2-yl)-1H-pyrazolo[3,4-b]pyridine-4-carboxylate (CAS 1011398-16-5)
- Ethyl 2-(3-cyclopropyl-6-(thiophen-2-yl)-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetate (CAS 1018051-77-8)
- 2-(3-Cyclopropyl-6-(5-ethylthiophen-2-yl)-4-(trifluoromethyl)-1h-pyrazolo[3,4-b]pyridin-1-yl)acetic acid (CAS 937606-22-9)
- Ethyl 2-(3-cyclopropyl-6-(1-methyl-1H-pyrazol-3-yl)-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetate (CAS 1173047-60-3)
- 6-Cyclopropyl-2-((2-(3-methoxyphenyl)-2-oxoethyl)thio)-4-(trifluoromethyl)nicotinonitrile (CAS 625377-48-2)
- 6-Cyclopropyl-2-{[2-(4-methoxyphenyl)-2-oxoethyl]sulfanyl}-4-(trifluoromethyl)pyridine-3-carbonitrile (CAS 625377-47-1)
- Cyclopropyl[4-(1-{[6-(trifluoromethyl)-3-pyridinyl]methyl}-4-piperidinyl)-1-piperazinyl]methanone (CAS 909670-30-0)
Recommended Standards
- Z-Phe-Ala-diazomethylketone (CAS 71732-53-1)
- 5-[(3-Methoxyphenyl)methyl]-7-(trifluoromethyl)-1H,3H,3aH,4H,5H-[1,3]thiazolo[3,4-a]quinoxalin-4-one (CAS 1024017-57-9)
- Bumetanide Impurity 10 (CAS CATO-C4X-198610)
- Propargyl-PEG4-beta-D-glucose (CAS 1397682-63-1)
- 5-(Trifluoromethyl)-4,5-dihydroisoxazol-5-ol (CAS 134219-67-3)
- (3,5-dimethylphenyl)methanesulfonyl chloride (CAS 352708-56-6)
- 4-Nitrobenzoxazole-2(3H)-thione (CAS 101495-34-5)
- Methyl 2-(4-(((benzyloxy)carbonyl)amino)bicyclo[2.2.2]Octan-1-yl)acetate (CAS 2231675-54-8)
- 3-Amino-6-fluoro-2-methoxybenzoic Acid Methyl Ester (CAS 1268830-91-6)
- (E)-N-Acetyl-N-desmethyl Doxepin (CAS 250331-54-5)
- 2,2,2-trideuterioethanamine (CAS 6118-19-0)
- (1,3-Thiazol-5-yl)methyl N-(2-chlorophenyl)carbamate (CAS 338981-78-5)
- 4-Methyl-5-(2-methyl-3-nitrophenyl)-4H-1,2,4-triazole-3-thiol (CAS 924841-96-3)
- Fibrinopeptide A, human TFA (CAS 61533-47-9)
Why CATO?
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