4-Chloro-1-((4-chlorophenoxy)methyl)-1H-pyrazole-3-carboxylic acid CAS 1006488-87-4

Purity 97%+In StockPharmaceutical Standards
CAS No.1006488-87-4
Molecular FormulaC11H8Cl2N2O3
Molecular Weight287.10 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

4-Chloro-1-((4-chlorophenoxy)methyl)-1H-pyrazole-3-carboxylic acid CAS 1006488-87-4 chemical structure

Description

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

4-Chloro-1-((4-chlorophenoxy)methyl)-1H-pyrazole-3-carboxylic acid (CAS 1006488-87-4) is a high-purity analytical reference standard with the molecular formula C11H8Cl2N2O3 and a molecular weight of 287.10 g/mol.

4-Chloro-1-((4-chlorophenoxy)methyl)-1H-pyrazole-3-carboxylic acid (C11H8Cl2N2O3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC11H8Cl2N2O3
Molecular Weight287.10 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, ethanol, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)8.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1988
Halogen ContentCl-containing
Nitrogen Atoms2

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