methyl 4-chloro-5-(chlorosulfonyl)-2-fluorobenzoate CAS 1154149-29-7
| CAS No. | 1154149-29-7 |
| Molecular Formula | C8H5Cl2FO4S |
| Molecular Weight | 287.09 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of methyl 4-chloro-5-(chlorosulfonyl)-2-fluorobenzoate is closely related to a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies methyl 4-chloro-5-(chlorosulfonyl)-2-fluorobenzoate (CAS 1154149-29-7), a certified reference material (molecular formula C8H5Cl2FO4S, MW 287.09 g/mol) for analytical method development and quality control.
The molecular framework of methyl 4-chloro-5-(chlorosulfonyl)-2-fluorobenzoate (C8H5Cl2FO4S) is characterized by a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures methyl 4-chloro-5-(chlorosulfonyl)-2-fluorobenzoate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H5Cl2FO4S |
| Molecular Weight | 287.09 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | F/Cl-containing |
| Sulfur Atoms | 1 |
Related methyl Standards
- Methyl 2-chloro-5-(chlorosulfonyl)-4-fluorobenzoate (CAS 1154155-49-3)
- methyl 5-chloro-3-(chlorosulfonyl)-2-fluorobenzoate (CAS 1154155-65-3)
- 4-Chloro-1-((4-chlorophenoxy)methyl)-1H-pyrazole-3-carboxylic acid (CAS 1006488-87-4)
- 4-Chloro-6-cyano-2-(difluoromethyl)pyridine-3-sulfonyl chloride (CAS 1805257-86-6)
- 4-Chloro-2-cyano-5-(difluoromethyl)pyridine-3-sulfonyl chloride (CAS 1805370-50-6)
- 4-Chloro-5-cyano-3-(difluoromethyl)pyridine-2-sulfonyl chloride (CAS 1805370-55-1)
- 4-Chloro-6-cyano-5-(difluoromethyl)pyridine-3-sulfonyl chloride (CAS 1805981-12-7)
- 2-Chloro-n-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]propanamide (CAS 731011-87-3)
Recommended Standards
- (3,4-Dichlorophenyl)(2,4-difluorophenyl)methanone (CAS 1096909-62-4)
- (3,5-Dichloro-2,4-difluorophenyl)(phenyl)methanone (CAS 1094311-96-2)
- 2-Amino-5-(trifluoromethyl)phenylboronic Acid Pinacol Ester (CAS 1058062-64-8)
- 2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-5-(trifluoromethyl)aniline (CAS 1196972-92-5)
- 4-(3-Methylphenyl)-1,2,3,6-tetrahydropyridine (CAS 71916-52-4)
- 1-Oxaspiro[5.5]undecan-4-one (CAS 1339866-28-2)
- N-(6-thioxo-1,6-dihydropyridazin-3-yl)propionamide (CAS 1447965-77-6)
- 2-(1H-Benzo[d]imidazol-2(3H)-ylidene)-1H-indene-1,3(2H)-dione (CAS 63786-62-9)
- (R)-3-(Allyloxy)pyrrolidine hydrochloride (CAS 1478194-93-2)
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- (4E)-4-[(Dimethylamino)methylidene]-1-[4-(trifluoromethoxy)phenyl]-3-(trifluoromethyl)-4,5-dihydro-1H-pyrazol-5-one (CAS 338403-22-8)
- (5E)-5-(2,1,3-Benzothiadiazol-4-ylmethylene)-2-mercapto-3-phenyl-3,5-dihydro-4H-imidazol-4-one (CAS 1142201-49-7)
- Methyl 3-(4-methylbenzenesulfonyl)-2-oxo-2H-chromene-6-carboxylate (CAS 895645-57-5)
- Neuropeptide W-23 (rat) (CAS 383415-89-2)
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