Methyl 2-chloro-5-(chlorosulfonyl)-4-fluorobenzoate CAS 1154155-49-3
| CAS No. | 1154155-49-3 |
| Molecular Formula | C8H5Cl2FO4S |
| Molecular Weight | 287.09 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Methyl 2-chloro-5-(chlorosulfonyl)-4-fluorobenzoate is closely related to a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies Methyl 2-chloro-5-(chlorosulfonyl)-4-fluorobenzoate (CAS 1154155-49-3), a certified reference material (molecular formula C8H5Cl2FO4S, MW 287.09 g/mol) for analytical method development and quality control.
Owing to a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system, Methyl 2-chloro-5-(chlorosulfonyl)-4-fluorobenzoate is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 287.09 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures Methyl 2-chloro-5-(chlorosulfonyl)-4-fluorobenzoate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H5Cl2FO4S |
| Molecular Weight | 287.09 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | F/Cl-containing |
| Sulfur Atoms | 1 |
Related Methyl Standards
- methyl 4-chloro-5-(chlorosulfonyl)-2-fluorobenzoate (CAS 1154149-29-7)
- methyl 5-chloro-3-(chlorosulfonyl)-2-fluorobenzoate (CAS 1154155-65-3)
- 4-Chloro-1-((4-chlorophenoxy)methyl)-1H-pyrazole-3-carboxylic acid (CAS 1006488-87-4)
- 4-Chloro-6-cyano-2-(difluoromethyl)pyridine-3-sulfonyl chloride (CAS 1805257-86-6)
- 4-Chloro-2-cyano-5-(difluoromethyl)pyridine-3-sulfonyl chloride (CAS 1805370-50-6)
- 4-Chloro-5-cyano-3-(difluoromethyl)pyridine-2-sulfonyl chloride (CAS 1805370-55-1)
- 4-Chloro-6-cyano-5-(difluoromethyl)pyridine-3-sulfonyl chloride (CAS 1805981-12-7)
- 2-Chloro-n-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]propanamide (CAS 731011-87-3)
Recommended Standards
- (3,4-Dichlorophenyl)(2,4-difluorophenyl)methanone (CAS 1096909-62-4)
- 2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-5-(trifluoromethyl)aniline (CAS 1196972-92-5)
- (3,5-Dichloro-2,4-difluorophenyl)(phenyl)methanone (CAS 1094311-96-2)
- 5-(2-Bromo-4-fluorophenyl)-5-methylimidazolidine-2,4-dione (CAS 1251925-16-2)
- 1-(2-(Thiophen-2-yl)ethyl)-1h-1,2,4-triazol-3-amine (CAS 1339927-50-2)
- 2-Bromo-6-(dimethoxymethyl)pyridine (CAS 128507-76-6)
- 1-Cyano-2-(isoquinolin-1(2H)-ylidene)ethyl acetate (CAS 56434-18-5)
- Methyl 5-oxobicyclo[2.2.2]oct-2-ene-2-carboxylate (CAS 1956327-72-2)
- 5-Ethynyl-4-methylthiazole (CAS 111600-93-2)
- 2-Amino-5-tert-butylphenol (CAS 1199-47-9)
- 1-(2-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}ethyl)-3-[(4-chlorophenyl)sulfanyl]pyrrolidine-2,5-dione (CAS 303151-59-9)
- (2S)-1-(Pyridin-2-yl)pyrrolidine-2-carboxylic acid (CAS 1104077-35-1)
- Ethyl 5-[1-(tert-butoxycarbonyl)piperidin-4-yl]-1H-indole-2-carboxylate (CAS 1603833-77-7)
- Semaglutide Impurity 145 (CAS CATO-C4X-2226145)
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