Phenoxybenzamine EP Impurity B CAS 101-45-1
| CAS No. | 101-45-1 |
| Molecular Formula | C18H23NO2 |
| Molecular Weight | 285.38 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 285.38 g/mol gives Phenoxybenzamine EP Impurity B distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Phenoxybenzamine EP Impurity B (CAS 101-45-1) is a certified pharmaceutical impurity reference standard with the molecular formula C18H23NO2 and a molecular weight of 285.38 g/mol.
Structurally, Phenoxybenzamine EP Impurity B (C18H23NO2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 8.0, corresponding to approximately 8 ring(s) or double-bond equivalent(s). With a molecular weight of 285.38 g/mol, it falls into the medium-molecular-weight range. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Phenoxybenzamine EP Impurity B under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C18H23NO2 |
| Molecular Weight | 285.38 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Nitrogen Atoms | 1 |
Related Phenoxybenzamine Standards
- Phenoxybenzamine Impurity 4 (CAS 76805-26-0)
- Phenoxybenzamine Impurity 3 (CAS 2512203-93-7)
- Phenoxybenzamine - API Standards (CAS 59-96-1)
- Phenoxybenzamine EP Impurity A (CAS 902273-13-6)
- Phenoxybenzamine-d5 (CAS 1188265-52-2)
- Phenoxybenzamine EP Impurity C (CAS 854881-53-1)
- Phenoxybenzamine Impurity A (CAS 68157-86-8)
- Phenoxybenzamine-D5 Hydrochloride (CAS 1329838-45-0)
Recommended Standards
- tert-Butyl 4-(4-ethynylphenyl)piperidine-1-carboxylate (CAS 1009640-15-6)
- (3-Ethoxy-4-methoxybenzyl)(2-phenylethyl)amine (CAS 101781-84-4)
- (R)-(-)-Metalaxyl-d6 (CAS 1398112-32-7)
- Adamantan-1-ylmethyl 3-aminobenzoate (CAS 1020241-84-2)
- Irbesartan Impurity 4 (CAS CATO-C4X-16664)
- Triptorelin Impurity 4 (CAS CATO-C4X-18624)
- Linagliptin impurity 139 (CAS 2137744-33-1)
- (4-(4-Fluorophenoxy)phenyl)boronic acid (CAS 361437-00-5)
- Hexyl 2-(4-bromophenyl)-8-methylquinoline-4-carboxylate (CAS 355419-71-5)
- 3-({3-[3-(4,5-Dihydro-1H-imidazol-2-ylamino)-propyl]-1-methyl-1H-indazole-6-carbonyl}-amino)-2-(4-oxazol-2-yl-benzenesulfonylamino)-propionic acid (CAS 1231017-08-5)
- (1H-Benzo[d][1,2,3]triazol-1-yl)(furan-3-yl)methanone (CAS 521305-02-2)
- N-((1-Ethyl-5-fluoro-3-methyl-1H-pyrazol-4-yl)methyl)-1-methyl-1H-pyrazol-3-amine hydrochloride (CAS 1855939-36-4)
- Ethyl 4-[3-(isopropylamino)-2,5-dioxopyrrolidin-1-yl]benzoate (CAS 1048957-09-0)
- Valosin Peptide (VQY), porcine (CAS 99510-37-9)
Why CATO?
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