Phenoxybenzamine Impurity 4 CAS 76805-26-0
| CAS No. | 76805-26-0 |
| Molecular Formula | C18H24N2O |
| Molecular Weight | 284.40 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Phenoxybenzamine Impurity 4 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies Phenoxybenzamine Impurity 4 (CAS 76805-26-0), a pharmacopoeial impurity reference standard (molecular formula C18H24N2O, MW 284.40 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, Phenoxybenzamine Impurity 4 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 284.40 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C18H24N2O |
| Molecular Weight | 284.40 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1978 |
| Nitrogen Atoms | 2 |
Related Phenoxybenzamine Standards
- Phenoxybenzamine EP Impurity B (CAS 101-45-1)
- Phenoxybenzamine Impurity 3 (CAS 2512203-93-7)
- Phenoxybenzamine - API Standards (CAS 59-96-1)
- Phenoxybenzamine EP Impurity A (CAS 902273-13-6)
- Phenoxybenzamine-d5 (CAS 1188265-52-2)
- Phenoxybenzamine EP Impurity C (CAS 854881-53-1)
- Phenoxybenzamine Impurity A (CAS 68157-86-8)
- Phenoxybenzamine-D5 Hydrochloride (CAS 1329838-45-0)
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Why CATO?
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- 130,000+ catalog items in stock, COA supplied with every batch
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