Ethyl 6-((4-(benzo[d][1,3]dioxol-5-ylmethyl)piperazin-1-yl)methyl)-2-oxo-4-phenyl-1,2,3,4-tetrahydropyrimidine-5-carboxylate CAS 1010259-15-0
| CAS No. | 1010259-15-0 |
| Molecular Formula | C26H30N4O5 |
| Molecular Weight | 478.54 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Ethyl 6-((4-(benzo[d][1,3]dioxol-5-ylmethyl)piperazin-1-yl)methyl)-2-oxo-4-phenyl-1,2,3,4-tetrahydropyrimidine-5-carboxylate is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Ethyl 6-((4-(benzo[d][1,3]dioxol-5-ylmethyl)piperazin-1-yl)methyl)-2-oxo-4-phenyl-1,2,3,4-tetrahydropyrimidine-5-carboxylate (CAS 1010259-15-0), molecular formula C26H30N4O5 and molecular weight 478.54 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of Ethyl 6-((4-(benzo[d][1,3]dioxol-5-ylmethyl)piperazin-1-yl)methyl)-2-oxo-4-phenyl-1,2,3,4-tetrahydropyrimidine-5-carboxylate (C26H30N4O5) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C26H30N4O5 |
| Molecular Weight | 478.54 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Nitrogen Atoms | 4 |
Related Ethyl Standards
- 3-(N-(Benzo[d][1,3]dioxol-5-yl)sulfamoyl)-N-(2-(2-methyl-1H-benzo[d]imidazol-1-yl)ethyl)benzamide (CAS 920882-44-6)
- N-(Benzo[d][1,3]dioxol-5-yl)-2-((5-(4-chlorophenyl)-4-(p-tolyl)-4H-1,2,4-triazol-3-yl)thio)acetamide (CAS 477330-34-0)
- N-(benzo[d]thiazol-2-yl)-2-((3-cyano-6-methyl-4-(thiophen-3-yl)-5,6,7,8-tetrahydro-1,6-naphthyridin-2-yl)thio)acetamide (CAS 340813-94-7)
- 2-((4-(Benzo[d][1,3]dioxol-5-yl)-1-phenyl-1H-imidazol-2-yl)sulfonyl)-N-(4-fluorophenyl)acetamide (CAS 892279-77-5)
- 5-(Benzo[d][1,3]dioxol-5-ylmethylene)-2-((2-(2-methylpiperidin-1-yl)-2-oxoethyl)thio)-3-(p-tolyl)-3,5-dihydro-4H-imidazol-4-one (CAS 854128-16-8)
- 2-((4-(Benzo[d][1,3]dioxol-5-yl)-3-cyano-6-phenylpyridin-2-yl)thio)-N-phenylpropanamide (CAS 333777-91-6)
- (E)-5-(benzo[d][1,3]dioxol-5-ylmethylene)-2-(4-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)piperazin-1-yl)-3,5-dihydro-4H-imidazol-4-one (CAS 865659-46-7)
- (4-(Benzo[d]thiazol-2-yl)piperazin-1-yl)(1-(thiophen-2-ylsulfonyl)piperidin-4-yl)methanone (CAS 900001-14-1)
Recommended Standards
- Hydrocortisone Impurity 33 (CAS 77106-62-8)
- tert-butyl (2R,4R)-2-((2-aminophenyl)carbamoyl)-4-(3-(4-cyanophenyl)ureido)piperidine-1-carboxylate (CAS 1095173-26-4)
- 3348-03-6 6-Carboxyfluorescein diacetate Spiro(isobenzofuran-1(3H),9'-(9H)xanthene)-6-carboxylic acid, 3',6'-bis(acetyloxy)-3-oxo- Spiro(phthalan-1,9'-xanthene)-6-carboxylic acid, 3',6'-dihydroxy-3-oxo-, diacetate 6-Carboxy-3',6'-diacetylfluorescein 6-Cfda (CAS 3348-03-6)
- 1-Piperidinecarboxylic acid, 4-[[5-(aminocarbonyl)-2-[[4-(2-oxazolyl)phenyl]amino]-4-pyridinyl]amino]-, 1,1-dimethylethyl ester (CAS 1227488-28-9)
- 2-Amino-3,3-dimethylcyclohex-1-ene-1-carbonitrile (CAS 15595-72-9)
- Methiothepin Maleate (CAS 19728-88-2)
- Ethyl 1,4-bis(4-chlorophenyl)-6-methyl-1H,4H,7H-pyrazolo[3,4-b]pyridine-5-carboxylate (CAS 339100-90-2)
- Sulfur, homopolymer (CAS 9035-99-8)
- 4-Methyl-6-(trifluoromethyl)-1H-pyrazolo[4,3-c]pyridine (CAS 340809-53-2)
- 3-[(pentan-3-yl)amino]propanenitrile (CAS 55619-08-4)
- (R)-2-(3-Chlorophenyl)-2,5-dihydrothiophene-3-carbaldehyde (CAS 1255188-96-5)
- Bis(1,2,3,4,5-pentamethylcyclopenta-2,4-dien-1-yl)strontium (CAS 112379-48-3)
- 1-Methoxy-4-(methylthio)benzene (CAS 1879-16-9)
- Palmitoyl Tetrapeptide-7 (CAS 221227-05-0)
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