Ritonavir EP Impurity K CAS 1010809-39-8
| CAS No. | 1010809-39-8 |
| Molecular Formula | C28H35N3O5S |
| Molecular Weight | 525.66 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Ritonavir EP Impurity K (CAS 1010809-39-8) is a certified pharmaceutical impurity reference standard with the molecular formula C28H35N3O5S and a molecular weight of 525.66 g/mol.
The molecular framework of Ritonavir EP Impurity K (C28H35N3O5S) is characterized by a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Ritonavir EP Impurity K meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C28H35N3O5S |
| Molecular Weight | 525.66 g/mol |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Ritonavir Standards
- Ritonavir EP Impurity J (CAS 162849-95-8)
- Ritonavir EP Impurity B (CAS 765875-58-9)
- Ritonavir EP Impurity F (CAS 1010809-61-6)
- Ritonavir Impurity 61 (CAS CATO-C4X-175161)
- Ritonavir EP Impurity D (CAS 144142-33-6)
- Ritonavir EP Impurity H (CAS 1010809-43-4)
- Ritonavir EP Impurity C (CAS 1010808-43-1)
- Ritonavir Impurity 60 (CAS 2454100-44-6)
Recommended Standards
- Pikromycin (CAS 19721-56-3)
- Darunavir Impurity 37 (CAS 159005-61-5)
- Chromoionophore IV (CAS 124522-01-6)
- Ro 0437626 (CAS 134362-79-1)
- Raltitrexed Impurity 9 (CAS 132462-57-8)
- Folic Acid Impurity 73 (CAS CATO-C4X-139573)
- Apremilast Impurity 77 (CAS CATO-C4X-100977)
- 3-[4-(propan-2-yl)phenyl]-1,2-oxazol-5-amine (CAS 1020996-98-8)
- 4-(Trifluoromethyl)-1,2,3,6-tetrahydropyridine (CAS 790646-62-7)
- 2,4-Dimethyl-6-oxo-1-phenyl-1,6-dihydropyridine-3-carboxylic acid (CAS 70506-54-6)
- Methyl 5-methyl-4-((3-nitro-1h-pyrazol-1-yl)methyl)isoxazole-3-carboxylate (CAS 1011350-32-5)
- CHMFL-ABL-053, >98% (HPLC) (CAS 1808287-83-3)
- N-(3-(1H-Imidazol-1-yl)propyl)-2,5-dimethyl-3-phenylpyrazolo[1,5-a]pyrimidin-7-amine (CAS 850751-43-8)
- Semaglutide impurity 85 (CAS CATO-C4X-222685)
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