Apremilast Impurity 77 CAS CATO-C4X-100977
| CAS No. | CATO-C4X-100977 |
| Molecular Formula | C13H18O6S |
| Molecular Weight | 302.34 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO supplies Apremilast Impurity 77 (CAS CATO-C4X-100977), a pharmacopoeial impurity reference standard (molecular formula C13H18O6S, MW 302.34 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system, Apremilast Impurity 77 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 302.34 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), Apremilast Impurity 77 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C13H18O6S |
| Molecular Weight | 302.34 g/mol |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Sulfur Atoms | 1 |
Related Apremilast Standards
- Apremilast Impurity 123 (CAS CATO-C4X-1009123)
- Apremilast Impurity 76 (CAS CATO-C4X-100976)
- Apremilast Impurity 122 (CAS CATO-C4X-1009122)
- Apremilast Impurity 35 (CAS CATO-C4X-100935)
- Apremilast Impurity 51 (CAS 2097600-16-1)
- Apremilast impurity 64 (CAS CATO-C4X-100964)
- Apremilast Impurity 56 (CAS 1284768-38-2)
- Apremilast Impurity 70 (CAS CATO-C4X-100970)
Recommended Standards
- p-Methoxyphenyl 1-thio-b-D-galactopyranoside (CAS 41341-62-2)
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- Roflumilast Impurity 56 (CAS CATO-C4X-108456)
- Metoclopramide impurity 01 (CAS 82689-92-7)
- Levocarnitine Impurity N22 (CAS 10457-99-5)
- Dexamethasone Impurity 117 (CAS CATO-C4X-1165117)
- 5-tert-butyl-1H-imidazole-4-carboxylic acid (CAS 714273-88-8)
- Ethyl 6-nitro-2-oxo-1,2-dihydroquinoline-3-carboxylate (CAS 85870-48-0)
- 5-(Methoxymethyl)-1-methylpyridin-2-one (CAS 2140327-26-8)
- N-2-Propyn-1-yl-4-(trifluoromethyl)benzenamine (CAS 233272-89-4)
- 5-Chloroquinolin-8-yl (2-chlorophenyl)carbamate (CAS 20842-60-8)
- 2-chloro-3-(3--(trifluoromethyl)phenyl)propanal (CAS 807667-31-8)
- Tirzepatide Impurity 20 (CAS CATO-C4X-324020)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com