6-(4-chlorophenyl)-1-(2-fluorophenyl)-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid CAS 1011397-66-2
| CAS No. | 1011397-66-2 |
| Molecular Formula | C19H11ClFN3O2 |
| Molecular Weight | 367.76 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 367.76 g/mol gives 6-(4-chlorophenyl)-1-(2-fluorophenyl)-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
6-(4-chlorophenyl)-1-(2-fluorophenyl)-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid (CAS 1011397-66-2) is a high-purity analytical reference standard with the molecular formula C19H11ClFN3O2 and a molecular weight of 367.76 g/mol.
Based on its molecular formula C19H11ClFN3O2, 6-(4-chlorophenyl)-1-(2-fluorophenyl)-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 367.76 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 6-(4-chlorophenyl)-1-(2-fluorophenyl)-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C19H11ClFN3O2 |
| Molecular Weight | 367.76 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
Related chlorophenyl Standards
- 1-(4-Chlorophenyl)-5-[(E)-[(4-fluorophenyl)methylidene]amino]-6-imino-2-oxo-1,2,3,6-tetrahydropyrimidine-4-carbonitrile (CAS 1048915-26-9)
- 2-[(4-Chlorophenyl)amino]-4-(4-nitrophenyl)-6-oxo-1,6-dihydropyrimidine-5-carbonitrile (CAS 1348555-04-3)
- 4-(2-Chlorophenyl)-5-methyl-2-(3-(trifluoromethyl)benzyl)-2,4-dihydro-3H-1,2,4-triazol-3-one (CAS 861205-97-2)
- 4-(3-Chlorophenyl)-3-methyl-1-{[3-(trifluoromethyl)phenyl]methyl}-4,5-dihydro-1H-1,2,4-triazol-5-one (CAS 860786-42-1)
- 4-(4-Chlorophenyl)-3-methyl-1-{[3-(trifluoromethyl)phenyl]methyl}-4,5-dihydro-1H-1,2,4-triazol-5-one (CAS 860786-62-5)
- 6-(2-Chlorophenyl)-2-morpholino-4-(trifluoromethyl)nicotinonitrile (CAS 478049-43-3)
- 6-(4-Chlorophenyl)-2-morpholino-4-(trifluoromethyl)nicotinonitrile (CAS 338749-81-8)
- 4-[(4-Chlorophenyl)sulfanyl]-2-(pyridin-2-yl)-6-(trifluoromethyl)pyrimidine (CAS 338418-08-9)
Recommended Standards
- n-(2-Chlorobenzyl)-2-(2-(trifluoromethyl)-1h-benzo[d]imidazol-1-yl)acetamide (CAS 478048-07-6)
- 5-[(E)-[(2-Chloro-6-fluorophenyl)methylidene]amino]-6-imino-2-oxo-1-phenyl-1,2,3,6-tetrahydropyrimidine-4-carbonitrile (CAS 1159976-68-7)
- Dinitrato(1,10-phenanthroline)copper(II) (CAS 19319-88-1)
- 5-(4-Isopropylphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carbonyl chloride (CAS 865412-31-3)
- UB 165 Fumarate (CAS 200432-86-6)
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- 3-Oxohexanedioic Acid Diethyl Ester (CAS 7149-59-9)
- 3-(Aminomethyl)-1-benzhydrylazetidin-3-ol (CAS 151097-26-6)
- 212890-35-2 2H-Pyran, 2-[(1R)-1-[2-(2,4-difluorophenyl)oxiranyl]ethoxy]tetrahydro- CTK0J7763 (CAS 212890-35-2)
- Toxaphene (CAS 8001-35-2)
- 1,8-Dihydro-Pyrrolo[3,2-g]indazole-3-carboxylic acid (CAS 865886-90-4)
- tert-Butyl 4-(aminomethyl)-1H-indole-1-carboxylate hydrochloride (CAS 1401425-19-1)
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