n-(2-Chlorobenzyl)-2-(2-(trifluoromethyl)-1h-benzo[d]imidazol-1-yl)acetamide CAS 478048-07-6

Purity 97%+In StockPharmaceutical Standards
CAS No.478048-07-6
Molecular FormulaC17H13ClF3N3O
Molecular Weight367.75 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

n-(2-Chlorobenzyl)-2-(2-(trifluoromethyl)-1h-benzo[d]imidazol-1-yl)acetamide CAS 478048-07-6 chemical structure

Description

The occurrence of n-(2-Chlorobenzyl)-2-(2-(trifluoromethyl)-1h-benzo[d]imidazol-1-yl)acetamide is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

n-(2-Chlorobenzyl)-2-(2-(trifluoromethyl)-1h-benzo[d]imidazol-1-yl)acetamide (CAS 478048-07-6) is a high-purity analytical reference standard with the molecular formula C17H13ClF3N3O and a molecular weight of 367.75 g/mol.

The molecular framework of n-(2-Chlorobenzyl)-2-(2-(trifluoromethyl)-1h-benzo[d]imidazol-1-yl)acetamide (C17H13ClF3N3O) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC17H13ClF3N3O
Molecular Weight367.75 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)11.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2025
Halogen ContentF/Cl-containing
Nitrogen Atoms3

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