1-(2,4-difluorophenyl)-5-thien-2-yl-1H-pyrazole-3-carboxylic acid CAS 1013980-01-2
| CAS No. | 1013980-01-2 |
| Molecular Formula | C14H8F2N2O2S |
| Molecular Weight | 306.29 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 306.29 g/mol gives 1-(2,4-difluorophenyl)-5-thien-2-yl-1H-pyrazole-3-carboxylic acid distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
1-(2,4-difluorophenyl)-5-thien-2-yl-1H-pyrazole-3-carboxylic acid (CAS 1013980-01-2), molecular formula C14H8F2N2O2S and molecular weight 306.29 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 1-(2,4-difluorophenyl)-5-thien-2-yl-1H-pyrazole-3-carboxylic acid (C14H8F2N2O2S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 1-(2,4-difluorophenyl)-5-thien-2-yl-1H-pyrazole-3-carboxylic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C14H8F2N2O2S |
| Molecular Weight | 306.29 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related difluorophenyl Standards
- (2Z)-3-[(2,4-Difluorophenyl)amino]-3-hydroxy-2-[(Z)-thiophene-2-carbonyl]prop-2-enenitrile (CAS 866151-82-8)
- 1-(2,4-Difluorophenyl)-3-(thiophen-2-yl)-1H-pyrazole-5-carboxylic acid (CAS 618382-86-8)
- 2-(2,3-Difluorophenyl)amino-4-(2-fluorophenyl)thiazole (CAS 887267-14-3)
- 2-(2,3-Difluorophenyl)amino-4-(3-fluorophenyl)thiazole (CAS 887267-09-6)
- 2-(2,4-Difluorophenyl)amino-4-(2-fluorophenyl)thiazole (CAS 887267-16-5)
- 2-(2,4-Difluorophenyl)amino-4-(3-fluorophenyl)thiazole (CAS 887267-11-0)
- 2-(2,5-Difluorophenyl)amino-4-(2-fluorophenyl)thiazole (CAS 887267-15-4)
- 2-(2,5-Difluorophenyl)amino-4-(3-fluorophenyl)thiazole (CAS 887267-10-9)
Recommended Standards
- Topiroxostat Impurity 26 (CAS CATO-C4X-105526)
- N4-(2-Fluorophenyl)-N2-(furan-2-ylmethyl)-L-asparagine (CAS 1098630-83-1)
- Fluconazole Impurity 37 (CAS CATO-C4X-101937)
- Methyl 5-(((4-fluorophenyl)amino)methyl)-3-hydroxy-4-(hydroxymethyl)picolinate (CAS 1198621-18-9)
- 4-[(2-Chloro-4-formyl-6-methoxyphenoxy)methyl]benzoic acid (CAS 428826-63-5)
- 1-(4-Chlorophenethyl)-3-(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)thiourea (CAS 502579-32-0)
- 3-Perylenecarboxaldehyde (CAS 35438-63-2)
- 4-(tert-Butyl)-N-(5-chloro-2-(1H-1,2,4-triazol-1-yl)phenyl)benzenesulfonamide (CAS 868269-06-1)
- 4-(Benzenesulfonyl)-2-methyl-3-phenyl-1,2-oxazolidine (CAS 339096-72-9)
- 1-(Furan-2-ylmethyl)-5-oxopyrrolidine-3-carboxamide (CAS 910443-32-2)
- RMC6236 Intermediate 28 (CAS CATO-CIM-103916)
- Glutathione Impurity 10 (CAS CATO-C4X-118510)
- N-(4-Fluorobenzyl)-2-methoxyethanamine hydrochloride (CAS 1158735-47-7)
- Acetyl decapeptide-3 (CAS 935288-50-9)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com