Topiroxostat Impurity 26 CAS CATO-C4X-105526
| CAS No. | CATO-C4X-105526 |
| Molecular Formula | C15H10N6O2 |
| Molecular Weight | 306.28 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Topiroxostat Impurity 26.
Topiroxostat Impurity 26 (CAS CATO-C4X-105526) is a certified pharmaceutical impurity reference standard with the molecular formula C15H10N6O2 and a molecular weight of 306.28 g/mol.
The molecular framework of Topiroxostat Impurity 26 (C15H10N6O2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C15H10N6O2 |
| Molecular Weight | 306.28 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 6 |
Related Topiroxostat Standards
- Topiroxostat Impurity 30 (CAS CATO-C4X-105530)
- Topiroxostat Impurity 56 (CAS CATO-C4X-105556)
- Topiroxostat Impurity 14 (CAS CATO-C4X-105514)
- Topiroxostat Impurity 16 (CAS CATO-C4X-105516)
- Topiroxostat Impurity 55 (CAS CATO-C4X-105555)
- Topiroxostat Impurity 54 (CAS CATO-C4X-105554)
- Topiroxostat impurity 72 (CAS CATO-C4X-105572)
- Topiroxostat impurity 73 (CAS CATO-C4X-105573)
Recommended Standards
- Fluconazole Impurity 37 (CAS CATO-C4X-101937)
- 1-(2,4-difluorophenyl)-5-thien-2-yl-1H-pyrazole-3-carboxylic acid (CAS 1013980-01-2)
- Diethyl2-phthalimidomalonate-2-13c (CAS 88596-93-4)
- N4-(2-Fluorophenyl)-N2-(furan-2-ylmethyl)-L-asparagine (CAS 1098630-83-1)
- Posaconazole Impurity 18(R,S,S,R) (CAS 213381-06-7)
- Mirabegron Impurity 34 (CAS 83304-13-6)
- Eltrombopag Impurity 45 (CAS CATO-C4X-119845)
- ETHYL 2-(3,4-DIHYDROXYPHENYL)ACETATE (CAS 83112-21-4)
- 2-((6-Amino-2-methylpyrimidin-4-yl)amino)benzoic acid (CAS 1219545-58-0)
- (2-Bromocyclopentyl)benzene (CAS 859178-03-3)
- Cefdinir Impurity 72 (CAS CATO-C4X-121072)
- Dicyclohexyl(2'-isopropyl-[1,1'-biphenyl]-2-yl)phosphane (CAS 251320-85-1)
- (5,6-Dihydroimidazo[2,1-b][1,3]thiazol-3-ylmethyl)amine dihydrochloride (CAS 940292-36-4)
- Tirzepatide Impurity 18 (CAS CATO-C4X-324018)
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