4-[(2-Chloro-4-formyl-6-methoxyphenoxy)methyl]benzoic acid CAS 428826-63-5
| CAS No. | 428826-63-5 |
| Molecular Formula | C16H13ClO5 |
| Molecular Weight | 320.72 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 4-[(2-Chloro-4-formyl-6-methoxyphenoxy)methyl]benzoic acid is closely related to a flavonoid core, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 4-[(2-Chloro-4-formyl-6-methoxyphenoxy)methyl]benzoic acid (CAS 428826-63-5), a certified reference material (molecular formula C16H13ClO5, MW 320.72 g/mol) for analytical method development and quality control.
Structurally, 4-[(2-Chloro-4-formyl-6-methoxyphenoxy)methyl]benzoic acid (C16H13ClO5) contains a flavonoid core, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 10.0, corresponding to approximately 10 ring(s) or double-bond equivalent(s). With a molecular weight of 320.72 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C16H13ClO5 |
| Molecular Weight | 320.72 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
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Recommended Standards
- 3-((2-Chloro-4-formyl-6-methoxyphenoxy)methyl)benzoic acid (CAS 428466-43-7)
- 5-((4-Chlorophenyl)thio)-1-methyl-3-(trifluoromethyl)-1H-pyrazole-4-carbaldehyde (CAS 321533-70-4)
- 2-Chloro-4-formyl-6-methoxyphenyl 4-methoxybenzoate (CAS 443730-99-2)
- 5-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methyl}thiophene-2-carboxamide (CAS 321432-70-6)
- rel-((2S,4S)-4-Amino-6-nitro-1,2,3,4-tetrahydroquinolin-2-yl)-2-methylpropan-1-ol hydrochloride (CAS 1345011-38-2)
- 4,6-Dibromo-1H-pyrrolo[3,2-c]pyridine (CAS 2089314-91-8)
- 1-(2,4-Dihydroxyphenyl)-2-(2-methoxyphenyl)ethanone (CAS 92549-46-7)
- (3-Propoxyphenyl)acetic acid (CAS 900704-18-9)
- 2-[(4-nitrobenzene)sulfinyl]acetic acid (CAS 3406-71-1)
- 2-Chloro-1-[chloro(difluoro)methoxy]-3-(trifluoromethyl)benzene (CAS 1417567-93-1)
- Ethyl(E)-6-chlorohex-2-enoate (CAS 107408-34-4)
- N-(3-((6-Acetamidopyridin-3-yl)oxy)-4-methylphenyl)-3-(4-fluorophenyl)-2-oxoimidazolidine-1-carboxamide (CAS 1020536-01-9)
- 1-[(2-Chloro-1,3-thiazol-5-yl)methyl]-4-[3-(trifluoromethyl)phenyl]piperazine (CAS 477848-01-4)
- Semaglutide impurity 286 (CAS CATO-C4X-2226286)
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