Methotrexate Impurity 41 CAS 101810-76-8
| CAS No. | 101810-76-8 |
| Molecular Formula | C15H20N2O5 |
| Molecular Weight | 308.33 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Methotrexate Impurity 41 (CAS 101810-76-8) is a certified pharmaceutical impurity reference standard with the molecular formula C15H20N2O5 and a molecular weight of 308.33 g/mol.
Based on its molecular formula C15H20N2O5, Methotrexate Impurity 41 contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 308.33 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO manufactures Methotrexate Impurity 41 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C15H20N2O5 |
| Molecular Weight | 308.33 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1986 |
| Nitrogen Atoms | 2 |
Related Methotrexate Standards
- Methotrexate Impurity 23 (CAS CATO-C4X-115423)
- Methotrexate impurity 48 (CAS CATO-C4X-115448)
- Methotrexate impurity 7 (CAS CATO-C4X-115447)
- Methotrexate Impurity 74 (CAS CATO-C4X-115474)
- Methotrexate Impurity 75 (CAS CATO-C4X-115475)
- Methotrexate Impurity 76 (CAS CATO-C4X-115476)
- Methotrexate Impurity 70 (CAS CATO-C4X-115470)
- Methotrexate Impurity 77 (CAS CATO-C4X-115477)
Recommended Standards
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com