2-Chloro-1-(4-(2-fluorobenzoyl)piperazin-1-yl)ethanone CAS 1018574-21-4
| CAS No. | 1018574-21-4 |
| Molecular Formula | C13H14ClFN2O2 |
| Molecular Weight | 284.71 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures 2-Chloro-1-(4-(2-fluorobenzoyl)piperazin-1-yl)ethanone under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
2-Chloro-1-(4-(2-fluorobenzoyl)piperazin-1-yl)ethanone (CAS 1018574-21-4), molecular formula C13H14ClFN2O2 and molecular weight 284.71 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 2-Chloro-1-(4-(2-fluorobenzoyl)piperazin-1-yl)ethanone (C13H14ClFN2O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 7.0, corresponding to approximately 7 ring(s) or double-bond equivalent(s). With a molecular weight of 284.71 g/mol, it falls into the medium-molecular-weight range. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C13H14ClFN2O2 |
| Molecular Weight | 284.71 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related Chloro Standards
- 2-Chloro-1-(4-(4-fluorobenzoyl)piperazin-1-yl)ethanone (CAS 1018525-90-0)
- 3-(4-Chloro-2-fluorophenyl)-1-oxa-3,8-diazaspiro[4.5]Decan-2-one (CAS 1335220-63-7)
- 5-Chloro-2-pyridin-4-ylquinoline-4-carboxylic acid (CAS 1144500-08-2)
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- Methyl 4-(2-(1-chloro-2-ethoxy-2-oxoethylidene)hydrazinyl)benzoate (CAS 1207062-38-1)
- 5-(6-Chloro-2-methoxypyridin-3-yl)-5-isopropyloxazolidine-2,4-dione (CAS 1227827-90-8)
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Recommended Standards
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- Avatrombopag Impurity 18 (CAS 958457-83-5)
- 4-(2,4-Difluorophenoxy)butane-1-sulfonyl chloride (CAS 1375068-02-2)
- 1,3,7-Triazaspiro[4.5]decane-2,4-dione hydrochloride (CAS 28937-09-9)
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- Ethyl 4,7-dichloroquinazoline-2-carboxylate (CAS 1189106-09-9)
- 4-(2-(2-Hydroxy-3,5-dimethylphenyl)-2-oxoethyl)piperidine-2,6-dione (CAS 526-02-3)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com