Famotidine EP Impurity I CAS 1020719-36-1
| CAS No. | 1020719-36-1 |
| Molecular Formula | C8H14N6O4S3 |
| Molecular Weight | 354.43 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Famotidine EP Impurity I.
Famotidine EP Impurity I (CAS 1020719-36-1) is a certified pharmaceutical impurity reference standard with the molecular formula C8H14N6O4S3 and a molecular weight of 354.43 g/mol.
Famotidine EP Impurity I (C8H14N6O4S3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Famotidine EP Impurity I meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H14N6O4S3 |
| Molecular Weight | 354.43 g/mol |
| Purity | >80% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Nitrogen Atoms | 6 |
| Sulfur Atoms | 3 |
Related Famotidine Standards
- Famotidine Impurity 11 (CAS 90237-03-9)
- Famotidine Impurity 32 (CAS 154754-59-3)
- Famotidine Impurity 56 (CAS CATO-C4X-139256)
- Famotidine Impurity 57 (CAS CATO-C4X-139257)
- Famotidine impurity 59 (CAS CATO-C4X-139259)
- Famotidine-d4 (Major) (CAS CATO-C4X-139217)
- Famotidine-13C-d3 (CAS 2744683-81-4)
- Famotidine-13C3 (CAS 1185241-48-8)
Recommended Standards
- Olanzapine Impurity 58 (CAS CATO-C4X-117858)
- (4Z)-3-tert-Butyl-4-[(naphthalen-1-yl)methylidene]-1-phenyl-4,5-dihydro-1H-pyrazol-5-one (CAS 1024754-31-1)
- N-Mesityl-2-((5-(pyridin-3-yl)-1,3,4-oxadiazol-2-yl)thio)acetamide (CAS 332930-17-3)
- 9,9'-Bianthracene (CAS 1055-23-8)
- Ritonavir EP Impurity K (CAS 1010809-39-8)
- Salbutamol Impurity 133 (CAS CATO-C4X-1176133)
- Famotidine impurity 66 (CAS 7259-54-3)
- 6,8-Dichlorobenzo[d][1,2,3]triazin-4(3H)-one (CAS 60233-65-0)
- (S)-5,6,7,8-Tetrahydroisoquinolin-5-amine (CAS 502612-42-2)
- 2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)ethan-1-amine hydrochloride (CAS 2377609-24-8)
- (5-Fluoro-2-((methylthio)methoxy)phenyl)boronic acid (CAS 958454-07-4)
- 4-Fluoro-N-(2-fluorobenzyl)benzamide (CAS 895366-06-0)
- 70028-88-5 A836742 phenyl-(3,4,5-trifluorophenyl)methanone phenyl-[3,4,5-tris(fluoranyl)phenyl]methanone (CAS 70028-88-5)
- Peptide 435 (CAS CATO-CPTD788435)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com