Doxofylline Impurity 20 CAS 1021-65-4
| CAS No. | 1021-65-4 |
| Molecular Formula | C11H16N4O2 |
| Molecular Weight | 236.27 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Based on its molecular formula C11H16N4O2, Doxofylline Impurity 20 contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 236.27 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO supplies Doxofylline Impurity 20 (CAS 1021-65-4), a pharmacopoeial impurity reference standard (molecular formula C11H16N4O2, MW 236.27 g/mol) used for the identification and quantification of trace impurities in APIs.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Doxofylline Impurity 20 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H16N4O2 |
| Molecular Weight | 236.27 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Nitrogen Atoms | 4 |
Related Doxofylline Standards
- Doxofylline Impurity 40 (CAS 23146-07-8)
- Doxofylline Impurity 12 (CAS 652-37-9)
- Doxofylline Impurity 28 (CAS 62637-09-6)
- Doxofylline Impurity 31 (CAS CATO-C4X-151331)
- Doxofylline Impurity 1 (CAS 1429636-74-7)
- Doxofylline impurity 46 (CAS CATO-C4X-151346)
- Doxofylline Impurity 10 (CAS CATO-C4X-151310)
- Doxofylline Impurity 33 (CAS CATO-C4X-151333)
Recommended Standards
- Telmisartan Impurity 57 (CAS 884330-16-9)
- Oseltamivir Impurity 59 (CAS 722-97-4)
- Pregabalin Impurity 31 (CAS 185815-56-9)
- Paliperidone Impurity 160 (CAS CATO-C4X-1724160)
- Axitinib Impurity 85 (CAS 13959-26-7)
- Biapenem impurity 33 (CAS 155835-09-9)
- Selexipag Impurity 60 (CAS CATO-C4X-196160)
- 2-(3-Methylisoxazol-5-yl)acetohydrazide (CAS 859285-24-8)
- 3-(4-(tert-Butoxy)phenyl)-3-((tert-butoxycarbonyl)amino)propanoic acid (CAS 372144-20-2)
- 2,2-Dimethyl-1,3-dioxan-5-ol (CAS 3391-30-8)
- (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)(methyl)amino)hex-5-enoic acid (CAS 856412-21-0)
- 5-Chloro-8-methylquinoline (CAS 78941-95-4)
- Ethyl 6-(Cyclopropylamino)pyridazine-3-carboxylate (CAS 1823333-44-3)
- Insulin Degludec Impurity 25 (CAS CATO-C4X-215725)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com