4-Amino-1-[(2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one CAS 10212-20-1
| CAS No. | 10212-20-1 |
| Molecular Formula | C9H12FN3O4 |
| Molecular Weight | 245.21 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 4-Amino-1-[(2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
4-Amino-1-[(2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one (CAS 10212-20-1), molecular formula C9H12FN3O4 and molecular weight 245.21 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 4-Amino-1-[(2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one (C9H12FN3O4) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C9H12FN3O4 |
| Molecular Weight | 245.21 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1959 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Amino Standards
- 2-Amino-1-((2R,3S,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-4(1H)-one (CAS 1006872-82-7)
- 5-Amino-1-(3-fluorophenyl)-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one (CAS 1416345-37-3)
- (1-Amino-3-(2-methoxyphenyl)propan-2-yl)phosphonic acid (CAS 66291-65-4)
- 4-Amino-1-((2R,3S,4R,5R)-4-fluoro-3-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-2(1H)-one (CAS 26563-01-9)
- 5-Amino-1-(4-fluorophenyl)-1,5-dihydro-4h-pyrazolo[3,4-d]pyrimidin-4-one (CAS 941868-16-2)
- Methyl 3-amino-3-[4-(difluoromethoxy)phenyl]propanoate (CAS 1038338-50-9)
- Methyl 2-amino-3-(2-(difluoromethoxy)phenyl)propanoate (CAS 1404638-75-0)
- 3-(Cbz-amino)-1,1-difluoro-2-propanol (CAS 1429913-43-8)
Recommended Standards
- Cefixime Impurity C68 (CAS 74440-05-4)
- Capecitabine EP Impurity A (CAS 66335-38-4)
- N-(4-cyano-3-methylisoxazol-5-yl)-4-fluorobenzamide (CAS 478033-14-6)
- Capecitabine Impurity 16 (CAS CATO-C4X-102416)
- Methyl 2-((1H-benzo[d]imidazol-2-yl)methyl)benzoate (CAS 62513-27-3)
- 6-Chloro-5-iodo-1H-benzo[d]imidazole (CAS 1224445-06-0)
- Methyl 2-(1-(4-fluorobenzyl)piperidin-4-yl)acetate (CAS 174561-03-6)
- (3-phenyloxetan-3-yl)methanethiol (CAS 1904200-35-6)
- 3-Methoxy-2-methylacrylonitrile (CAS 63940-82-9)
- 2-Phenylpyrimidine-5-carboxylic Acid (CAS 122773-97-1)
- 4-Bromo-1,2-dimethyl-5-(quinoxalin-6-yl)-1H-pyrazol-3(2H)-one (CAS 1208320-93-7)
- 1-(3-Chloro-2,6-difluorophenyl)ethanamine (CAS 1337728-56-9)
- 2-(3-methoxypropoxy)-4-propoxybenzoic acid (CAS 1179243-44-7)
- Galanin-Like Peptide (rat) trifluoroacetate salt (CAS 245114-97-0)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com