Capecitabine Impurity 16 CAS CATO-C4X-102416
| CAS No. | CATO-C4X-102416 |
| Molecular Formula | C9H12FN3O4 |
| Molecular Weight | 245.21 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Capecitabine Impurity 16 (C9H12FN3O4) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO supplies Capecitabine Impurity 16 (CAS CATO-C4X-102416), a pharmacopoeial impurity reference standard (molecular formula C9H12FN3O4, MW 245.21 g/mol) used for the identification and quantification of trace impurities in APIs.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Capecitabine Impurity 16 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C9H12FN3O4 |
| Molecular Weight | 245.21 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Capecitabine Standards
- Capecitabine EP Impurity A (CAS 66335-38-4)
- Capecitabine Impurity 18 (CAS 71609-08-0)
- Capecitabine EP Impurity B (CAS 3094-09-5)
- Capecitabine Impurity 28 (CAS 862508-03-0)
- Capecitabine Impurity 19 (CAS CATO-C4X-102419)
- Capecitabine Impurity 12 (CAS 62211-93-2)
- Capecitabine Impurity 14 (CAS 76497-54-6)
- Capecitabine Impurity 41 (CAS CATO-C4X-102441)
Recommended Standards
- 4-Amino-1-[(2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one (CAS 10212-20-1)
- Pantoprazole Impurity 58 (CAS CATO-C4X-139958)
- Cefixime Impurity C68 (CAS 74440-05-4)
- 4-(Methylsulfonyl)-2-Nitrobenzoic Acid (CAS 110964-79-9)
- Butamirate Impurity N76 (CAS 92321-53-4)
- Osimertinib Impurity 17 (CAS CATO-C4X-204517)
- Cariprazine Impurity 41 (CAS 1957145-61-7)
- Benzyl (R)-2-amino-2-(3-(trifluoromethyl)bicyclo[1.1.1]Pentan-1-yl)acetate (CAS 1983347-20-1)
- 5-ethyl-2,3-dihydro-1H-1,3-benzodiazol-2-one (CAS 39513-23-0)
- 1,2,3,4-Tetrahydroquinoxalin-5-amine (CAS 163120-59-0)
- 5-(Difluoromethyl)-4-(trifluoromethyl)pyridin-2(1H)-one (CAS 1805274-85-4)
- 2-Butoxy-6-chloropyridin-4-amine (CAS 1346809-38-8)
- 1-(3-Methyl-[1,2,4]triazolo[4,3-a]pyrazin-8-yl)piperidin-4-amine (CAS 1492244-81-1)
- Semaglutide Impurity 160 (x TFA Salt) (CAS CATO-C4X-2226160)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com