Resmetirom impurity 66 CAS CATO-C4X-291266
| CAS No. | CATO-C4X-291266 |
| Molecular Formula | C13H13Cl2N3O |
| Molecular Weight | 298.17 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Resmetirom impurity 66 (CAS CATO-C4X-291266) is a certified pharmaceutical impurity reference standard with the molecular formula C13H13Cl2N3O and a molecular weight of 298.17 g/mol.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, Resmetirom impurity 66 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 298.17 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Resmetirom impurity 66 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C13H13Cl2N3O |
| Molecular Weight | 298.17 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Resmetirom Standards
- Resmetirom Impurity 62 (CAS CATO-C4X-291262)
- Resmetirom impurity 67 (CAS CATO-C4X-291267)
- Resmetirom Impurity 9 (CAS CATO-C4X-29129)
- Resmetirom Impurity 22 (CAS 125001-18-5)
- Resmetirom impurity 124 (CAS CATO-C4X-2912124)
- Resmetirom impurity 19 (CAS CATO-C4X-291219)
- Resmetirom Impurity 43 (CAS CATO-C4X-291243)
- Resmetirom Impurity 8 (CAS 1581304-46-2)
Recommended Standards
- Palbociclib Impurity 153 (CAS CATO-C4X-1125153)
- tert-Butyl (2-(2-(bromomethoxy)ethoxy)ethyl)carbamate (CAS 2858813-07-5)
- 4-Bromo-5-((2-(cyclohex-1-en-1-yl)ethyl)amino)pyridazin-3(2h)-one (CAS 1008351-60-7)
- N-[3-(1-Imidazolyl)propyl]-2,4-dichlorobenzamide (CAS 349092-52-0)
- para-Hydroxy Atorvastatin-d5 Calcium Salt (CAS 265989-45-5)
- Oxytetracycline EP Impurity B Hydrate (CAS 305833-60-7)
- Baricitinib Impurity 93 (CAS CATO-C4X-226093)
- N,N,1,1,2,2,3,3,4,4,4-undecadeuteriobutan-1-amine (CAS 748123-28-6)
- 5-Chloro-1-cyclopentyl-3-(trifluoromethyl)-1H-pyrazole (CAS 1437435-37-4)
- 1,3,(6,7)-Naphthalenetrisulfonic acid trisodium salt hydrate (CAS 123409-01-8)
- 3-Chloro-N-(2-oxothiolan-3-yl)benzamide (CAS 321521-88-4)
- Doxofylline Impurity 9 (CAS CATO-C4X-15139)
- (3R,4S)-1-(tert-butoxycarbonyl)-4-(3,4-dimethylphenyl)pyrrolidine-3-carboxylic acid (CAS 2227745-91-5)
- Epidermal Growth Factor Receptor Peptide (985-996) (CAS 96249-43-3)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com