N-(3-Chlorophenyl)-4-(trifluoromethyl)benzenesulfonamide CAS 1022777-49-6
| CAS No. | 1022777-49-6 |
| Molecular Formula | C13H9ClF3NO2S |
| Molecular Weight | 335.73 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of N-(3-Chlorophenyl)-4-(trifluoromethyl)benzenesulfonamide (C13H9ClF3NO2S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
N-(3-Chlorophenyl)-4-(trifluoromethyl)benzenesulfonamide (CAS 1022777-49-6) is a high-purity analytical reference standard with the molecular formula C13H9ClF3NO2S and a molecular weight of 335.73 g/mol.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures N-(3-Chlorophenyl)-4-(trifluoromethyl)benzenesulfonamide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C13H9ClF3NO2S |
| Molecular Weight | 335.73 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related N Standards
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- 4-(4-Chlorophenyl)-2-((4-fluorobenzyl)amino)-4-oxobutanoic acid (CAS 1025762-54-2)
- 2-{[(4-chlorophenyl)methyl]amino}-4-(4-fluorophenyl)-4-oxobutanoic acid (CAS 1032129-83-1)
- (Z)-3-(2-((4-chlorophenyl)thio)-5-nitrophenyl)acrylic acid (CAS 175278-51-0)
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Recommended Standards
- N-(2-Chloro-4-fluorobenzyl)-6-methyl-4-oxo-4,5-dihydro-[1,2,3]triazolo[1,5-a]pyrazine-3-carboxamide (CAS 1421462-81-8)
- 4-Difluoromethanesulfonamido-2-methoxybenzene-1-sulfonyl chloride (CAS 1041583-35-0)
- Sitafloxacin impurity 59 (CAS 1542764-78-2)
- 4-Chloro-n-(4-(trifluoromethyl)phenyl)benzenesulfonamide (CAS 107491-59-8)
- 2-Bromo-5-isopropoxypyridine (CAS 857992-23-5)
- 2-Ethyl-3-methylpyrazine (CAS 15707-23-0)
- 5,8-Difluoroquinolin-4-ol (CAS 874781-10-9)
- Ethyl 2-amino-3,5,6-trifluoroisonicotinate (CAS 259675-84-8)
- 1-((3-Bromobenzyl)oxy)-3,5-dimethylbenzene (CAS 1283769-52-7)
- (R)-1-(3-(Benzyl(ethyl)amino)piperidin-1-yl)-2-chloroethanone (CAS 1354002-34-8)
- N-(1-(3-bromophenyl)ethyl)cyclopropanamine hydrochloride (CAS 2367002-65-9)
- 16:0-18:1(n7) PC-IsoPure (CAS 132295-25-1)
- Methyl 2-(3,4,5-trifluorobenzoyl)benzoate (CAS 1443331-20-1)
- Semaglutide impurity 199 (CAS CATO-C4X-2226199)
Why CATO?
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